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Primordial Germ Cells

SOX15 - A Crucial Factor in the Generation of Human Primordial Germ Cell-Like Cells

The in-vitro differentiation of human embryonic stem cells into primordial germ cell-like cells reveals the importance of a SOX15-mediated regulatory network 

Activin A Aids ESC Differentiation into PGCLCs

ESCs cultured in the presence of activin A possess a robust ability to differentiate into PGCLCs

miRNA-GPCR Networks and Zebrafish Gonadal Renewal

Recent research from the laboratory of Jizhou Yan (Shanghai Ocean University, Shanghai, China) sought to delineate the regulatory networks controlling gonadal stem cell renewal in zebrafish.

Defining the Specification of Human Primordial Germ Cells: SOX17 Surprises!

Using a new strategy, researchers have successfully differentiated and studied human primordial germ cell like cells, uncovering the mechanisms which control germ cell specification in humans

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