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Periodontal Ligament Stem Cells

Engineered Periodontal Ligament Stem Cell-derived Exosomes as a New Therapy for Periodontitis

P2X7 receptor‐modified periodontal ligament stem cells reduce inflammation via an exosome‐mediated paracrine mechanism that may aid periodontitis treatment

Stem Cell Differentiation into Cementoblasts During Aging

New research identifies two different stem cell populations that can differentiate into cementoblasts in the periodontium

Regulation of Periodontal Ligament Stem Cell Differentiation

A new study reports on the requirement of distinct signaling pathways for the ligament‐fibroblastic and cementoblastic differentiation of human PDLSCs.

Exosomes from P2X7R Gene-modified Cells

Xu et al. now establish that P2X7R gene-modified cells can reverse inflammation‐mediated impairments in PDLSCs via their secreted products

M2 Macrophages Enhance Cementoblastic Differentiation

In a new STEM CELLS study, researchers led by Fa‐Ming Chen and Bei‐Min Tian (Fourth Military Medical University, Xi'an, China) sought to understand how polarized macrophage phenotypes influenc

Periodontal Ligament Stem Cells - A New and Effective means to Treat Optic Nerve Injury?

Treatment with human periodontal ligament stem cells in a rat model of optic nerve injury leads to enhanced retinal ganglion cell survival and axon regeneration

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