ESCs/iPSCs

A new study suggests that while mitochondrial replacement therapy may be successful in the treatment of mitochondrial disease, small amounts of mitochondrial carry-over can allow disease reappearance

A new study describing the differentiation of retinal ganglion cells from human pluripotent stem cells may provide a new tool to study optic neuropathies

New research highlights the importance of alternative splicing at various stages of iPSC reprogramming

Research suggests that iPSCs generated from older patient samples are more likely to carry higher levels of mitochondrial DNA damage which could affect their therapeutic application

Researchers successfully apply a microchamber culture strategy for mESCs which potentiates endogenous signaling to promote pluripotency

Using patient specific induced pluripotent stem cells, a new study shows that cell-based treatments for deafness may be a future possibility

Researchers describe how multilayered ocular structures generated from iPSCs may provide a patient-specific means to treat forms of blindness

A Stem Cells study shows that modulating a microenvironmental factor can alter smooth muscle cell differentiation from ESCs; knowledge which could boost vascular therapies.

New research in SCTM describes a safe and effective new strategy for the treatment of type 1 diabetes using induced pluripotent stem cell-derived progenitors

A new study describes the successful retinal differentiation of induced pluripotent stem cells generated using mRNA, a strategy which may be more clinically relevant than traditional strategies