ESCs/iPSCs

Research suggests that iPSCs generated from older patient samples are more likely to carry higher levels of mitochondrial DNA damage which could affect their therapeutic application

Researchers successfully apply a microchamber culture strategy for mESCs which potentiates endogenous signaling to promote pluripotency

Using patient specific induced pluripotent stem cells, a new study shows that cell-based treatments for deafness may be a future possibility

Researchers describe how multilayered ocular structures generated from iPSCs may provide a patient-specific means to treat forms of blindness

A Stem Cells study shows that modulating a microenvironmental factor can alter smooth muscle cell differentiation from ESCs; knowledge which could boost vascular therapies.

New research in SCTM describes a safe and effective new strategy for the treatment of type 1 diabetes using induced pluripotent stem cell-derived progenitors

A new study describes the successful retinal differentiation of induced pluripotent stem cells generated using mRNA, a strategy which may be more clinically relevant than traditional strategies

New research describes a novel role for the REST transcription factor in the cardiac-specific differentiation of embryonic stem cells

Researchers describe the first evidence of the production of functional sperm-like cells from mouse embryonic stem cells

New research describes how the pluripotency-associated factor DPPA5 promotes the maintenance of the pluripotent state