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Mimicking Ocular Development and Treating Corneal Blindness using iPSCs

Researchers describe how multilayered ocular structures generated from iPSCs may provide a patient-specific means to treat forms of blindness

Boosting Vascular Therapies by Modulating the Microenvironment?

A Stem Cells study shows that modulating a microenvironmental factor can alter smooth muscle cell differentiation from ESCs; knowledge which could boost vascular therapies.

A Safe and Effective Means to Produce and Transplant iPSC-Derived Progenitors?

New research in SCTM describes a safe and effective new strategy for the treatment of type 1 diabetes using induced pluripotent stem cell-derived progenitors

Retinal Differentiation of mRNA-Reprogrammed iPSCs – Safe and Efficient!

A new study describes the successful retinal differentiation of induced pluripotent stem cells generated using mRNA, a strategy which may be more clinically relevant than traditional strategies

Cardiac Differentiation of ESCs - A New Role for REST

New research describes a novel role for the REST transcription factor in the cardiac-specific differentiation of embryonic stem cells

First Description of Pluripotent Stem Cell-derived Functional Sperm

Researchers describe the first evidence of the production of functional sperm-like cells from mouse embryonic stem cells

DPPA5 Aids NANOG Protein in Human ESCs

New research describes how the pluripotency-associated factor DPPA5 promotes the maintenance of the pluripotent state

Self-Renewal of Differentiated Cells – An “Enhancer” of Cell Therapies?

New research describes how differentiated cells undergo the process of self-renewal via specific enhancer element usage

New Probe Aims to Aid Pluripotent Stem Cell Culture

The application of a new fluorescent probe may enhance our ability to maintain high quality pluripotent stem cell cultures

Cell Encapsulation Boosts Stem Cell Therapy for Type 1 Diabetes

A new study suggests that encapsulation of ESC-derived cells with a modified seaweed product could enhance survival and lower immune responses after transplantation

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