ESCs/iPSCs

Elevated glucosylsphingosine levels activate mTORC1 to interfere with normal lysosomal biogenesis and autophagy in iPSC-derived neurons

CYCLIND1 mRNA transfection helps to repair DNA during reprogramming to pluripotency, resulting in a genetically stable footprint in human iPSCs

iPSC‐derived smooth muscle cells enhance the therapeutic efficacy of iPSC‐derived endothelial cells after cotransplantation in a murine hindlimb ischemia model

A combination of eight transcription factors that orchestrate oocyte growth can also prompt the conversion of mouse embryonic stem cells into oocyte-like cells

A small-molecule compound that activates mitochondrial respiration can rescue defects to neuronal differentiation in iPSCs carrying mutant mitochondrial DNA

Neurotrophin‐3 secreted from human ESC-derived cardiovascular progenitor cells may protect from  ischemia/reperfusion injury

While transplanted human iPSC-derived skeletal muscle cells become infiltrated by immune cells after transplantation, this does not negatively impact engraftment

A study reports a microfluidic “heart-on-a-chip” system and its validation via an analysis of responses to electrical stimulation and drug administration

GPC4 downregulation prompts efficient differentiation of iPSCs into dopaminergic neurons

JAK2 mediates the epigenetic control of pluripotency in mouse embryonic stem cells