ESCs/iPSCs

A comparative study indicates that immature dopaminergic neurons derived from hPSCs represent the ideal cell type for replacement therapy in Parkinson’s Disease

A single-cell RNA sequencing study of liver organoids provides insight into the signaling processes that control three-dimensional organ development 

A new study shows that exposure to blood flow hemodynamics can improve the maturation of vascular cells derived from induced pluripotent stem cells

Two exciting technologies collide to facilitate the modeling of a rare genetic disease and provide a means to discover new treatment strategies

Studies into sex determination using induced pluripotent stem cells leads to a potential strategy to conserve an endangered species

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

Researchers describe a new chemical cocktail that enables pluripotent stem cells to form embryonic and extraembryonic tissues

A new study finds that progressive electrophysiological and morphological maturation of transplanted iPSC-derived neural cells occurs over long-time periods in vivo

A new study learns that the activation of the innate immune system enhances the reprogramming of somatic cells into other fates