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How do we Test for Immunogenicity of Human iPSC-Derived Cells?

Researchers demonstrate that currently used systems assessments of human iPSC immunogenicity are not sufficient.

Creating Tolerance for Human Embryonic Stem Cell Graft Derivatives

Short term T-cell mediated immune response blockade promotes the functionality of hESC-derivative grafts in immune-competent mice.

Simple Substrates Aid Stem Cell Differentiation

Cheap and simple growth substrates are discovered to aid differentiation of stem cells as compared to more complex and expensive alternatives

Quick and Easy Recipe for Mature Neurons from iPSCs

A quick and easy differentiation protocol for neural stem cells and their derivatives from human induced pluripotent stem cells

Making cardiomyocytes from Pluripotent Cells: Pure and Simple!

A large scale differentiation system combined with metabolomic purification yields pure and functional cardiomyocytes from human pluripotent stem cells

Creation of Human Intestine from Human Pluripotent Stem Cells

An in vivo maturation step mediates the generation of organoids resembling mature intestinal tissue from human pluripotent stem cells

Enhancing ESC-derived Therapies for Age Related Disorders

Improved production of retinal cells from embryonic stem cells brings this therapy closer to the clinic.

Higher Developmental State Reached in Human Pluripotent Cells

Human pluripotent stem cells brought to their highest developmental state, carrying with them the promise of the study of early human development and advances in regenerative medicine

iPSC Production – Select Your Factors Wisely

More is not always better in reprogramming, as researchers show that a set of factors which reprogram cells with low efficiency are developmentally superior to other more “efficient” reprogramming cocktails.

Stem Cells Get Motoring!

Motor neuron diseases encompass a range of neurological disorders that affect the muscles and movement of the body. These disorders are caused by the progressive degeneration of motor neurons, often leading to paralysis and ultimately death in patients. Can a stem cell-based strategy provide replacement cells?


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