A new study highlights the unexpectedly dynamic nature of bivalent chromatin domains in stem cells and shows how the cell cycle mediates their formation.
Using a mouse model with a human immune system, researchers find that not all induced pluripotent stem cell derivatives are equal, immunologically speaking.
Disruption of the antigen-presenting system in hESCs generates cells with reduced immunogenicity, in what could be the first step towards creating immuneprivileged, and universally accepted cells/tissues.
Exciting new study combining iPSCs and 3D organoid cultures discovers that stem cell amplification due to the overexpression of FOXG1 may lie at the root of autism spectrum disorder.
Generating inducible gene knockout in human pluripotent stem cells may open up a new level of understanding the roles of genes and groups of genes in pluripotency and differentiation.
Researchers demonstrate the pro-regenerative effects of exosomes derived from induced pluripotent stem cells and highlight a possible role for exosomes in tissue repair.