ESCs/iPSCs

Researchers demonstrate that nicotinamide adenine dinucleotide supports the pluripotent state of human embryonic stem cells through the regulation of metabolism

Research suggests that the actin cytoskeleton can significantly impact the differentiation of human pluripotent stem cells into functional pancreatic β cells

A recent STEM CELLS Translational Medicine study from the laboratory of

A new STEM CELLS study from Songcheng Zhu and Jiuhong Kang (Tongji University, Shanghai, Chi

Researchers demonstrate that tissue inhibitor of metalloproteinase proteins may inhibit PSC‐derived teratoma formation through cell cycle arrest and increased apoptosis

A new review article from the laboratory of Ming‐Tao Zhao (Nationwide Children's Hospital/Ohio State University College of

Researchers describe a novel strategy for the isolation of pure populations of subtype-specific cardiomyocytes from differentiating cultures of induced pluripotent stem cells

Culturing cells from prostate cancer biopsies to study mechanisms of disease and discover novel treatments suffers from many difficulties; however, a new study from the laboratory of Rakesh Heer

Researchers from the lab of Ton J.

Autosomal dominant polycystic kidney disease (ADPKD), the most common inherited kidney disease, leads to kidney failure in most patients. While mutations in the Polycystin 1 (PKD1) gene cause 85% of cases, we do not fully understand how dysregulation of PKD1 leads to cyst formation on a molecular level.