ESCs/iPSCs

A new study reports the efficient and rapid differentiation of human PSCs into a neural precursor population with early intermediate ectodermal characteristics

HDAC inhibitor identified as a Nakajo‐Nishimura syndrome treatment by screening using PSC‐derived monocytic cell lines

A novel and simple methodology an identify and enrich somatic cells correctly undergoing reprogramming into induced pluripotent stem cells

Functional engraftment of human iPSC-derived neurons into a human adult host neural network may boost the clinical translation of novel cerebral cortex treatments

An inhibitor of dihydroorotate dehydrogenase specifically induces elevated levels of cytotoxicity in mouse PSCs

Researchers use induced pluripotent stem cells grown and differentiated within an extracellular matrix bioink to develop a chambered muscle pump

A new report explores how the microRNA184/Wnt3 signaling pathway modulates the cardiac mesoderm differentiation of ESCs

Non-genetic methodologies to reduce undesirable proliferation represent a valuable tool when generating dopamine neurons from induced pluripotent stem cells

Sarcomeric maturation and the induction of adult-like function following TnI expression may foster the therapeutic application of in hiPSC‐derived cardiomyocytes

New lung organoid model allows the identification of primary cell‐intrinsic and secondary causes of congenital diaphragmatic hernia lung hypoplasia