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From Exploring CGI Protection to Epigenomic Editing in Pluripotent Stem Cells

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

The Safe, Effective, and Non-Invasive Production of Induced Pluripotent Stem Cells from Down Syndrome Patients

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

Chemical Cocktail Creates Extended Pluripotent Stem Cells

Researchers describe a new chemical cocktail that enables pluripotent stem cells to form embryonic and extraembryonic tissues

Long-term Neuronal Cell Transplant Study Highlights Long-Distance Neural Growth

A new study finds that progressive electrophysiological and morphological maturation of transplanted iPSC-derived neural cells occurs over long-time periods in vivo

Innate Immune Pathway Stimulation Enhances Reprogramming Strategies

A new study learns that the activation of the innate immune system enhances the reprogramming of somatic cells into other fates

Will an Enhanced Endothelial Cell Differentiation Strategy Leave CVDs “Quaking” in their Boots?

The overexpression of an RNA binding protein enhances endothelial cell differentiation from induced pluripotent stem cells and may improve the treatment of cardiovascular disease patients

Pluripotent Stem Cells Retain Innate Species-specific Developmental Timing

A new study indicates that the timing of the in vitro differentiation of pluripotent stem cells reflects species-specific rates of development

New Differentiation Strategy Aims to Boost Cell Therapies for Vascular Disease

A new study describes an improved protocol for the efficient differentiation of endothelial cells from pluripotent stem cell sources and highlights the importance of the MAPK and PI3K signaling pathways

Optimized Platform Boosts Studies of Rare Neurodevelopmental Disorders

A new study describes a quick and efficient means to generate, gene-edit, and differentiate induced pluripotent stem cells in order to study rare neurodevelopmental disorders

Totipotency – Just an miRNA Away?

A new study shows that the loss of a single microRNA is sufficient to endow mouse pluripotent stem cells with totipotent characteristics


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