ESCs/iPSCs

A study exploring DNA methylation processes has uncovered an exciting new means to edit the epigenome in pluripotent stem cells

A new means to generate Down Syndrome specific iPSCs may lead to enhanced cell-based treatments for associated pathologies and a deeper understanding of disease development

Researchers describe a new chemical cocktail that enables pluripotent stem cells to form embryonic and extraembryonic tissues

A new study finds that progressive electrophysiological and morphological maturation of transplanted iPSC-derived neural cells occurs over long-time periods in vivo

A new study learns that the activation of the innate immune system enhances the reprogramming of somatic cells into other fates

The overexpression of an RNA binding protein enhances endothelial cell differentiation from induced pluripotent stem cells and may improve the treatment of cardiovascular disease patients

A new study indicates that the timing of the in vitro differentiation of pluripotent stem cells reflects species-specific rates of development

A new study describes an improved protocol for the efficient differentiation of endothelial cells from pluripotent stem cell sources and highlights the importance of the MAPK and PI3K signaling pathways

A new study describes a quick and efficient means to generate, gene-edit, and differentiate induced pluripotent stem cells in order to study rare neurodevelopmental disorders

A new study shows that the loss of a single microRNA is sufficient to endow mouse pluripotent stem cells with totipotent characteristics