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ESCs/iPSCs

Organ Complementation highlights in vivo Contribution of PSCs to Bone-forming Cells

A study shows how human pluripotent stem cells form functional osteoblasts following transplantation into a mouse embryo engineered to lack a skeletal system

Overcoming infertility with Induced Pluripotent Stem Cell Reprogramming?

Researchers investigating sex chromosome trisomy discover that reprogramming patient cell samples may be an effective means to treat human infertility 

Preclinical Assessment for hESC-derived Oligodendrocyte Progenitor Cells for Cervical Spinal Cord Injury

An exciting new animal study suggests that oligodendrocyte progenitor cells derived from human ESCs are safe for the treatment of cervical spinal cord injury

Comparative Study Highlights Utility of iPSC-derived Cardiomyocytes

A cardiomyocyte showdown suggests that cells derived from different PSC sources demonstrate similar characteristics and functionality following transplantation

TEC-mediated FGF2 Secretion Controls hPSC Pluripotency

A new study describes the discovery of a novel regulator of basic fibroblast growth factor 2-mediated pluripotency

Stem Cell Therapy for Parkinson's Disease - Which Cell is Best?

A comparative study indicates that immature dopaminergic neurons derived from hPSCs represent the ideal cell type for replacement therapy in Parkinson’s Disease

 

Organoid Analysis Highlights the Intercellular Signaling Processes controlling Hepatogenesis

A single-cell RNA sequencing study of liver organoids provides insight into the signaling processes that control three-dimensional organ development 

iPSC-derived Vascular Cells Go with the Flow!

A new study shows that exposure to blood flow hemodynamics can improve the maturation of vascular cells derived from induced pluripotent stem cells

iPSCs and CRISPR/Cas9 Combine to Faithfully Model CoQ10 Deficiency

Two exciting technologies collide to facilitate the modeling of a rare genetic disease and provide a means to discover new treatment strategies

Saving an Endangered Species: iPSC Technology to the Rescue?!

Studies into sex determination using induced pluripotent stem cells leads to a potential strategy to conserve an endangered species

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