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STEM CELLS | STEM CELLS Translational Medicine
A new review summarizes advances in iPSC‐based modeling to explore glial cell involvement in neurodegenerative diseases
iPSC-derived AMD model used to investigate the interplay between lysosome function and complement activation in the hope of identifying therapeutic targets
The miR‐183/96/182 cluster controls retinal tissue morphogenesis and represents an important regulator of PAX6 expression
Modulating the miR‐184/Wnt3 pathway in embryonic stem cells may provide for the development of efficient cell therapies for the damaged heart
CDK8/19 Mediator components control pluripotent stem cell differentiation and self-renewal and regulate preimplantation naïve epiblast gene expression
Kanagaki et al. underscore the potential utility of iPSC-derived AT1cells in understanding their differentiation from AT2 cells in vitro.
A review summarizes in vitro models used in aortic disease research and provides guidance for the development of advanced models using iPSCs
New research identifies differences in the global chromatin landscape that occur during the cellular reprogramming of canine cells
iPSC‐derived smooth muscle cells enhance iPSC‐derived endothelial cells' therapeutic efficacy in peripheral artery disease
Adding islet-associated environmental cues could represent a promising route to enhance the function of hPSC‐derived beta cells