ESCs/iPSCs

A new review article stresses the importance of implementing complex 3D brain organoids derived from human induced pluripotent stem cells

An engineered morphogen signaling center within an embryonic stem cell aggregate supports the development of “embryoids” that exhibit germ layer development

An improved understanding of the role of TRPV4 in chondrogenesis may provide insight into the development of new therapeutic approaches

A new article discusses the potential of stem cell-derived pancreatic progenitors and matured insulin-producing cells to treat diabetes

A new review discusses the use of human pluripotent stem cell-derived cells and organoids in severe acute respiratory syndrome coronavirus 2 research

New research reports on "iBlastoids" - blastocyst-like structures formed from iPSCs that model several aspects of human blastocyst biology

A new study uncovers the detailed molecular bases of PRC1.6 function in mouse embryonic stem cells through an evaluation of MGA activity

Researchers report on naïve ESC-derived human "blastoids" and their applicability to the study of early human development, early pregnancy loss, and early developmental defects 

An exploration of the links between glucosphingolipid accumulation and mTORC1 activity in human induced pluripotent stem cell‐derived neurons from neuronopathic Gaucher disease patients

Reprogramming in the presence of CYCLIND1 overexpression allows for the more accurate and reliable generation of human iPSCs for disease modeling and clinical applications