ESCs/iPSCs

New findings establish the transplantation of embryonic stem cell-derived cardiomyocytes as an effective means to restore lost cardiac function in monkeys

New research establishes how partial reprogramming may be harnessed to promote wound healing by reducing skin fibrosis and scar formation

Two new studies in immortalized retinal pigment epithelial cells and induced pluripotent stem cells raise more concern regarding CRISPR-Cas9-based genome editing safety

A new study demonstrates how three-dimensional coculture of induced pluripotent stem cell-derived spinal motor neurons enhances both cell maturity and functionality

Chinese researchers discover of two small molecule compounds that enhance CRISPR-Cpf1-based genome engineering of human pluripotent stem cells

Researchers describing a novel induced-pluripotent stem cell model of ApoE4-related Alzheimer's disease highlight potentially exciting new treatment approaches

A new Cell study highlights the importance of two generally unappreciated mechanisms, splicing and protein synthesis, to the pluripotent state and the developing embryo

A new study from the Knoepfler laboratory reveals EBP1 as a major cofactor that influences the transcriptional activity of DPPA4 in pluripotent cells

A new study takes the field further towards the industrial-scale culture and safe and cost-effective clinical application of human pluripotent stem cells

Researchers studying the molecular mechanisms that control mitochondrial dynamics in pluripotent cells discover a role for the apoptosis-related protein MCL-1