ESCs/iPSCs

Systematic evaluation of methods to differentiate dopaminergic neurons from hPSCs identifies measures to improve comparisons and clinical translation

Immature hPSC-derived pancreatic β cell clustering in vitro promotes the generation of mature β cells that resemble their endogenous counterparts

New research highlights the influence of a GPCR effector on the maintenance of hESC pluripotency and the successful reprogramming of fibroblasts to hiPSCs 

Researchers describe how a risk locus impacts VSMC related genes expression, thereby influencing the risk of coronary artery disease and possibly other CVDs 

New research highlights the suitability of hepatocytes differentiated from cGMP human pluripotent stem cells for therapeutic applications in human patients

A new study shows how genome editing of induced pluripotent stem cells may pave the way for the development of in vitro chondrogenesis platforms

Researchers study human iPSC-derived neurons following transplantation into the mouse brain to understand healthy and diseased neuronal dynamics in vivo

A new study explores DNA methylation, imprinting barriers, and uniparental reproduction and reports the first generation of full-term bipaternal mice

Researchers discover that donor age, ancestry, and chromatin remodeling complex component expression significantly affect reprogramming efficiency

Researchers report the identification of small molecules that promote cardiomyogenesis through the TGFβ pathway and not the Wnt/β‐catenin pathway