ESCs/iPSCs

A new study demonstrates how three-dimensional coculture of induced pluripotent stem cell-derived spinal motor neurons enhances both cell maturity and functionality

Chinese researchers discover of two small molecule compounds that enhance CRISPR-Cpf1-based genome engineering of human pluripotent stem cells

Researchers describing a novel induced-pluripotent stem cell model of ApoE4-related Alzheimer's disease highlight potentially exciting new treatment approaches

A new Cell study highlights the importance of two generally unappreciated mechanisms, splicing and protein synthesis, to the pluripotent state and the developing embryo

A new study from the Knoepfler laboratory reveals EBP1 as a major cofactor that influences the transcriptional activity of DPPA4 in pluripotent cells

A new study takes the field further towards the industrial-scale culture and safe and cost-effective clinical application of human pluripotent stem cells

Researchers studying the molecular mechanisms that control mitochondrial dynamics in pluripotent cells discover a role for the apoptosis-related protein MCL-1

Researchers demonstrate how CRISPR/Cas9-mediated exon skipping, or myoediting, may rescue dystrophin function in a majority of Duchenne muscular dystrophy patients

A new study identifies a long non-coding RNA as an important barrier impeding the reprogramming of cells derived from old patients

A new study suggests that DNA methylation analysis of select gene promoters can identify the optimal pluripotent stem cell for bone repair strategies