ESCs/iPSCs

The function of the sphingosine‐1‐phosphate (S1P) signaling pathway in embryonic stem cells (ESCs) remains unclear; therefore, researchers led by Todd Evans

Age‐related macular degeneration (AMD), a multifactorial disease of primates, has confounded efforts that aim to model the disease in laboratory animals or during in vitro culture. However, researchers led by Mark A.

Research highlights the requirement for constant β‐catenin degradation via adenomatous polyposis coli activity to support human embryonic stem cell self-renewal

Culture of pluripotent stem cells within a microfluidic platform allows the exploration of the developmental processes taking place in the early human embryo

The ability of cells to communicate with their surroundings by producing different classes of extracellular vesicles (EVs) plays an important role in physiological and pathological processes. Now, researchers led by Richard A.

Researchers from the lab of Takahiro Ichiya (Tokyo Medical University, Tokyo, Japan) recently revealed an additional role for miR‐124a in the early development of mouse embryonic stem cells mESCs in a STEM CELLS

Induced pluripotent stem cell therapy reduces endothelial cell leakage after acute lung injury through a pathway involving TIMP‐1 and the FAK/Snail pathway

Generation of PSC-derived neuruloids hopes to provide insight into human development and a range of poorly understood human genetic diseases and pediatric cancers

The ablation of proliferative pluripotent stem cells (PSCs) before or after the transplantation of PSC-derivatives would significantly reduce associated risks, including teratoma formation.

In a recent STEM CELLS article, researchers from the laboratories of Guiying Wang and Jiuhon