ESCs/iPSCs

New research highlights the suitability of hepatocytes differentiated from cGMP human pluripotent stem cells for therapeutic applications in human patients

A new study shows how genome editing of induced pluripotent stem cells may pave the way for the development of in vitro chondrogenesis platforms

Researchers study human iPSC-derived neurons following transplantation into the mouse brain to understand healthy and diseased neuronal dynamics in vivo

A new study explores DNA methylation, imprinting barriers, and uniparental reproduction and reports the first generation of full-term bipaternal mice

Researchers discover that donor age, ancestry, and chromatin remodeling complex component expression significantly affect reprogramming efficiency

Researchers report the identification of small molecules that promote cardiomyogenesis through the TGFβ pathway and not the Wnt/β‐catenin pathway

An optimized differentiation strategy permits the large-scale production of retinal organoids that display light responsiveness and use in drug testing

Researchers discover a new cell surface glycoprotein that plays a crucial role in the stemness and proliferation of human embryonic stem cells

New findings establish the transplantation of embryonic stem cell-derived cardiomyocytes as an effective means to restore lost cardiac function in monkeys

New research establishes how partial reprogramming may be harnessed to promote wound healing by reducing skin fibrosis and scar formation