ESCs/iPSCs

A small-molecule compound that activates mitochondrial respiration can rescue defects to neuronal differentiation in iPSCs carrying mutant mitochondrial DNA

Neurotrophin‐3 secreted from human ESC-derived cardiovascular progenitor cells may protect from  ischemia/reperfusion injury

While transplanted human iPSC-derived skeletal muscle cells become infiltrated by immune cells after transplantation, this does not negatively impact engraftment

A study reports a microfluidic “heart-on-a-chip” system and its validation via an analysis of responses to electrical stimulation and drug administration

GPC4 downregulation prompts efficient differentiation of iPSCs into dopaminergic neurons

JAK2 mediates the epigenetic control of pluripotency in mouse embryonic stem cells

A new review highlights the significant achievements and challenges associated with iPSC‐based otic cell modeling

A new study confirms that alveolar type I cells present in induced pluripotent stem cell‐derived alveolar organoids closely resemble primary alveolar cells

In vitro models of human β‐cells and insulin secretion as powerful tools to study diabetes

Reduced GLI1 expression in ESCs by gene-editing leads to differentiation defects