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American Academy of Stem Cell Physicians Visit Capitol Hill to Discuss Patient Safety

MIAMISept. 23, 2019 - The American Academy of Stem Cell Physicians visited Capitol Hill on Thursday, Sept. 19, at an event hosted by Alliance for Cell Therapy Now, to meet with industry partners to discuss the future and direction of cell therapy in the United States.  

Surviving ‘butterfly disease’: long-term success of a new gene and stem-cell therapy for EB verified

MUNSTER (DE), December 2021 — The skin is the largest organ of the human body. But what if the skin “disintegrates” at just the slightest touch? This is exactly what happens with Epidermolysis bullosa (EB), sometimes also known by the name “butterfly disease.” This skin disease is based on genetic defects and, because there is no cure, it can be fatal, often even in young patients.

Doctoral student finds alternative cell option for organs-on-chips

COLLEGE STATION, TX (US), December 2021 — Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don’t exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

How the body uses fat to fight infection

NORWICH (UK), December 2021 — New research reveals how our immune cells use the body’s fat stores to fight infection. The research, published in Nature Communications, could help develop new approaches to treating people with bacterial infections.

How bone-bordering cells might help shape a skull

NEW YORK, NY (US), December 2021 —A skull is not one single bone but rather a collection of bone plates joined together early in development. In a study of mice, scientists at the Icahn School of Medicine at Mount Sinai showed how the activity of one gene, turned on in a newly discovered group of bone-bordering cells, might play an important role in shaping the skull.

Discovery of stem-like t cell in type 1 diabetes holds potential for improving cancer immunotherapy

NEW YORK, NY (US) — To an immunologist, autoimmune diseases like type 1 diabetes are the polar opposite of cancer. In the former, the immune system goes into overdrive and attacks the body’s own organs in a relentless manner, eventually causing disease; with cancer, the immune system shuts down and fails to mount an aggressive attack to stop cancer from forming.

Why does the immune system behave so differently in the two cases? No one knows.

Heart repair and regeneration after a heart attack — a review

BIRMINGHAM, AL (US), December 2021 – Twenty years ago, clinicians first attempted to regenerate a failing human heart by injecting muscle myoblasts into the heart during a bypass operation. Despite initial high hopes and multiple experimental and clinical studies since then, outcomes have been neutral or marginally positive for a wide variety of attempts to remuscularize an injured heart.

Testosterone-producing Leydig cells successfully generated from iPS cells

KOBE (JP), December 2021 — Researchers from Kobe University’s Graduate School of Science, Technology and Innovation/ Graduate School of Medicine have succeeded in generating Leydig cells from human iPS cells. Leydig cells are responsible for producing the male hormone testosterone, and it is hoped that Leydig cell transplants could someday serve as a treatment for late-onset hypogonadism. (Hypogonadism occurs when sex glands called gonads produce little, if any, sex hormones, resulting in low sex drive.)

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