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Limbal Stem Cells

Transplantation of Cultured Stem Cell as an Optimal Treatment for Limbal Stem Cell Deficiency

A comparison of limbal stem cell deficiency treatment approaches highlights autologous limbal stem cell transplantation as the optimal strategy for visual function recovery

Simple Limbal Epithelial Transplantation - A Review

A new review article from STEM CELLS Translational Medicine examines those studies

SPARC Promotes Limbal Stem Cell Proliferation

In a recent STEM CELLS article, researchers led by Jing Zhou (Shandong University, Shandong,

Limbal Stem Cell Versus Tissue Transplantation

Researchers led by Vincent M.

Trial Provides Impetus for Autologous Limbal Stem Cell Transplantation in Vision Threatening Disease

A phase I/II trial examines allogeneic corneal epithelial stem cells cultured on amniotic membrane at GMP standard for the treatment of bilateral LSCD

Corneal Epithelial Stem Cell Study Highlights Dry Eye as a Major Obstacle to Corneal Epithelial Wound Healing

Researchers exploring corneal epithelial stem cell therapy for vision loss highlight the deleterious effects of inflammation and dry eye to potential outcomes

New Cell Surface Markers May Boost Limbal Stem Cell-based Therapies

Researchers highlight the potential of cell markers for isolation of limbal stem cells and limbal epithelial progenitors towards possible therapeutic applications

CRISPR-Cas9 Genome Editing of Limbal Stem Cells Generates Faithful Model of Panocular Condition

Using CRISPR-Cas9 genome editing of limbal stem cells, researchers demonstrate the potential utility of PAX6 as a therapeutic tool for aniridia patients

Simple and Efficient Protocol Developed to Produce hPSC-Derived Corneal Cells

Researchers describe a quick and effective strategy to derive corneal cells from human pluripotent stem cells and highlight the importance of BMP signaling

Autologous oral mucosal epithelial cells in the treatment of limbal stem cell deficiency

Researchers demonstrate that autologous oral mucosal epithelial cells expanded under good manufacturing practice requirements can reverse limbal stem cell deficiency in injured eyes up to 24 months, representing an advance in ocular tissue regeneration and transplantation

 

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