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Colon Stem Cells

Isolation and in vitro expansion of human colonic stem cells

From Nature Medicine
By Stuart P. Atkinson

A paper recently published in Nature Medicine, described as a major advance for regenerative medicine, has reported for the first time the isolation and in vitro culture of stem cells from the adult human colon (CoSCs) (Jung and Sato et al). This achievement, from the group of Eduard Batlle at the Institute for Research in Biomedicine, Barcelona, achieved its success after over 10 years of intensive research into the characterization of the biology of the intestinal stem cells and its connection with cancer. The study, done in collaboration with renowned researchers Hans Clevers and María A. Blasco, represents a sub­stantial step forward toward the use of human CoSCs in regenerative medicine and toward understanding their role in pathology.

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