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Correcting Chromosomal Abnormalities in iPSCs via Chromosome Transplantation

Chromosome transplantation in iPSCs may allow for the correction of structural chromosome abnormalitiesthat other gene therapy approaches cannot tackle

Novel Approaches to Achieve Thymic Regeneration

Exciting new research from the laboratory of Marita Bosticardo (IRCCS San Raffaele Scientific Institute, Milan, Italy) provides proof‐of‐principle for a new approach toward thymic re

Review: Translating Stem Cells for Stroke Clinical Trials

A new Concise Review from the laboratory of Cesario V.

Novel Bioprinting Strategy Provides for Rapid and Precise Wound Healing

An innovative mobile skin bioprinting system integrates wound imaging with precise in-situ cell delivery to accelerate skin formation and wound healing

Kidney Tubuloids: A Fascinating New Member of the Organoid Family

A new study describes the generation of kidney tubuloids from human and mouse in the hope of providing a quick a versatile means to model function and disease

CRISPR-activation of SOX2 Promotes Corneal Endothelial Cell-mediated Wound Healing and Regeneration

New research describes how CRISPR-activation of SOX2 gene expression can enhance wound healing of the corneal endothelium and inhibit vision loss

Novel 3D Bioprinting Approach Generates Vascularized and Well-organized Cardiac Tissue Constructs

Advanced bioprinting technique employing iPSC-derived cardiomyocytes and endothelial cells generates cardiac tissue constructs with improved functionality

CRISPR/Cas9-based Exon Skipping Returns Dystrophin Expression to a Canine Model of DMD

Studies in an animal model of Duchenne muscular dystrophy highlight the in vivo utility of CRISPR/Cas9-based exon “skipping”-based treatment approaches

Homing CRISPR/Cas9 Technology to Barcode and Lineage Trace Mouse Development

A new CRISPR/Cas9 barcoding approach permits reconstruction of early mouse lineages and investigation of brain axis development

CRISPR Activation Strategy Takes Induced Pluripotent Stem Cell Generation to another Level

Targeting an embryo genome-activation motif permits the first generation of induced pluripotent stem cells via CRISPR activation of reprogramming factors


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