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Epitranscriptome Landscape of sncRNAs in Stem Cells

Researchers led by Abdulrahim Sajini brings us up to date regarding how the epitranscriptome will play critical roles in regenerative medicine and RNA‐based therapeutics in the near future

Neurotrophic Effects of Decellularized Muscles

Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue.

Efficacy Outcomes in Uncontrolled Trials

Interpretation of observed change in a continuous outcome measure as preliminary evidence of efficacy in the setting of an uncontrolled trial can lead to erroneous conclusions due to the effect of regression to the mean.

Stem Cell-derived Retinal Organoids: A Review

Retinal diseases that can lead to vision impairment or blindness currently suffer from a lack of effective treatment options.

Killers at The Crossroads

Adoptive cell therapy (ACT) as an approach to cancer treatment involves the administration of antitumor immune cells to target residual disease in patients after completion of chemo/radiotherapy. Currently, the identification and generation of antitumor effector cells that efficiently recognize tumor cells remain important barriers to the success of ACT in cancer clinical trials.

Can Targeting Cardiomyocyte Metabolism Improve Cardiac Regeneration?

Inhibiting fatty-acid utilization can reduce the reactive oxygen species-mediated DNA damage response and promote cardiomyocyte proliferation in the postnatal mouse heart

Single Cell Analyses Suggest Stressed out Organoids Do Not Match Up

A comparison of the transcriptomes of the developing human cortex and cortical organoids at the single-cell level provide evidence for stress-mediated differences

Alveolar War - The Rise of In Vitro Alveolar Models

Over the last decade, stem cell‐derived culture models of human lungs have garnered renewed interest as a means to recapitulate human lung tissues in a dish.

The Vision of the Regenerative Medicine Manufacturing Society

The Regenerative Medicine Manufacturing Society recently provided a Perspective article in

Vascularization for Regenerative Medicine – A Review

The promotion of blood vessel growth for therapeutic purposes remains a challenge both for the treatment of ischemia and the generation of functional tissue‐engineered grafts, as physiological angiogenesis represents an extraordinarily complex process.


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