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Technology

Developing Prime Editing in Organoids as a Modeling Tool and Treatment Strategy

An organoid-based study provides evidence for the considerable potential of prime editing in disease modeling and treatment but highlights a need for further innovation

Skin Fibroblasts Induce Local Nerve Regeneration

The activation of fibroblasts and their reprogramming into a neural cell-like state following wounding supports the regrowth of axons from local nerves

Cell Therapies in Cardiac Repair

A new review summarizes recent progress in the field of paracrine and stem cell-derived cardiomyocytes for cardiac repair and regeneration

StEMM and the Heart Stem Cell Niche

Researchers develop a new technique to evaluate the presence and localization of stem/progenitor cell niches in the heart

Comprehensive Evaluation of Cell Therapy for NICM

Meta-analysis supports the concept that cell therapy remains a promising therapeutic option for nonischemic dilated cardiomyopathy

New Advance Supports Extended Ex Vivo Mouse Embryo Development

A highly effective platform for the ex-utero culture of post-implantation mouse embryos permits the study of embryonic stages from before gastrulation till the hindlimb formation stage

Workforce Development in Regenerative Medicine

A new perspective article addresses workforce development in regenerative medicine

Analyzing PSC Culture with StemCellQC

Researchers report StemCellQC as a label-free video bioinformatics analysis tool for evaluating pluripotent stem cell morphology, quality, and dynamics during in vitro culture

Radiotherapy and the Immune System

A review discusses how ionizing radiation provokes tumor‐specific immune responses by inducing immunogenic cancer cell death and reshaping the tumor microenvironment

Organoid Technology – A Review

A new review discusses concerns regarding organoids, the methods available for organoid formation, and the types of reported human organoid models

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