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Adult Stem Cells

Adult Stem Cell Therapy and the Immune Response

Multipotent stem cells can alter the immune response to injury, limit the damage due to inflammation and thereby promote repair

MAPCs for Hypoxic-ischemic Cerebellar Injury

A recent article describes the reduction of cerebellar injury after asphyxia following systemic multipotent adult progenitor cell therapy

Corneal Stromal Stem Cell Transplantation Induces Recovery from Corneal Scarring

Corneal stromal stem cell therapy reverses liquid nitrogen-associated alterations in the cornea and restores corneal transparency and ameliorates vision loss

Sustainment of Prostate Luminal Cell Lineages

A new article now describes the critical role of Sox2 in maintaining the facultative bipotent differentiation capacity of Sca‐1+ prostate luminal cells.

Inner Ear Progenitor Cell Culture Comparison Reveals Novel Hearing Loss Treatment Approach

The RhoA-YAP-β‐catenin signaling axis senses and transduces mechanical cues from the extracellular matrix to promote the expansion of inner ear progenitor cells

Conjunctival Epithelial Stem Cells Enriched by p75

While surgical reconstruction of the conjunctiva represents the principal treatment approach, the lack of efficient methods for stem cell enrichment makes this approach challenging. 

Deciphering How Stress Influences Stem Cells and Tissue Regeneration

A study establishes that stressed mice suffer from the loss of melanocyte stem cells and the appearance of har greying, showing how physiological status can affect tissue regeneration

Expanding Inner Ear Progenitor Cells

The impact of extracellular matrix mechanical cues and mechanotransduction signaling on inner ear progenitor cell (IEPCs) fate remains relatively undescribed; however, researchers led by

Bone Marrow Mononuclear Cells for Ischemic Stroke

Researchers led by Sean I.

Capillary-Resident EphA7-Positive Multipotent Pericytes

A current lack of markers for multipotent pericytes limits our understanding of their pathophysiological roles; however, researchers from the lab of Jun-ichi Kawabe (Asahikawa Medical University, Hokkaido, Japan) have now described how the implementation of EphA7 (Eph Receptor A7)  as a  marker to isolate pericytes from the microvessels of mouse subcutaneous adipose tissues. Yoshida et al.


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