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Adult Stem Cells

Corneal Stromal Stem Cell Transplantation Induces Recovery from Corneal Scarring

Corneal stromal stem cell therapy reverses liquid nitrogen-associated alterations in the cornea and restores corneal transparency and ameliorates vision loss

Sustainment of Prostate Luminal Cell Lineages

A new article now describes the critical role of Sox2 in maintaining the facultative bipotent differentiation capacity of Sca‐1+ prostate luminal cells.

Inner Ear Progenitor Cell Culture Comparison Reveals Novel Hearing Loss Treatment Approach

The RhoA-YAP-β‐catenin signaling axis senses and transduces mechanical cues from the extracellular matrix to promote the expansion of inner ear progenitor cells

Conjunctival Epithelial Stem Cells Enriched by p75

While surgical reconstruction of the conjunctiva represents the principal treatment approach, the lack of efficient methods for stem cell enrichment makes this approach challenging. 

Deciphering How Stress Influences Stem Cells and Tissue Regeneration

A study establishes that stressed mice suffer from the loss of melanocyte stem cells and the appearance of har greying, showing how physiological status can affect tissue regeneration

Expanding Inner Ear Progenitor Cells

The impact of extracellular matrix mechanical cues and mechanotransduction signaling on inner ear progenitor cell (IEPCs) fate remains relatively undescribed; however, researchers led by

Bone Marrow Mononuclear Cells for Ischemic Stroke

Researchers led by Sean I.

Capillary-Resident EphA7-Positive Multipotent Pericytes

A current lack of markers for multipotent pericytes limits our understanding of their pathophysiological roles; however, researchers from the lab of Jun-ichi Kawabe (Asahikawa Medical University, Hokkaido, Japan) have now described how the implementation of EphA7 (Eph Receptor A7)  as a  marker to isolate pericytes from the microvessels of mouse subcutaneous adipose tissues. Yoshida et al.

Studying Neuronal Network Formation in Dissociated Cerebral Organoid Cultures

Researchers employ human cerebral organoids to evaluate patterns of neural network activity to investigate the functionality of human neuronal networks

 

Role of FRα in Glial De-differentiation

Previous research from the lab of Chandra Shekhar Mayanil (Stanley Manne Children's Research Institute, Chicago, IL, USA) established that Folate Receptor-α (FRα) translocates to the nucleus and upregulates the transcription of pluripotency-associated genes.

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