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Cardiac Stem Cells

ZIC2 Controls the Emergence of Human Heart Progenitors

To reveal the regulators that control the formation of human cardiac progenitor cells without bias, researchers led by Kenneth R.

New Mechanism Behind Stem Cell Therapy in the Damaged Heart Uncovered

A fascinating new study suggests that stem cell therapy induces an acute inflammatory-based wound-healing response that rejuvenates the infarcted area of the heart

Environmental Adaptation of Cardiac Interstitial Cells

The biological properties and functional activities of c‐Kit+ adult cardiac interstitial cells, or cCICs, continue to elude researchers despite decades of investigation; however, researchers led by

Predicting Cardiac Progenitor Cell Therapy Outcomes in the Failing Heart with miRNA Profiles

Researchers employ a computational modeling technique to establish a relationship between exosomal miRNA and responses in a rat myocardial infarction model

Electrical Stimulation of Pediatric CPCs

Cardiac‐derived progenitor cells (CPCs) have been widely studied as a cell‐based therapy for cardiac pathologies; however, they tend to display an age-related decline in therapeutic efficacy.

Discovery of Cardiac Progenitor Cell Proliferators

Small molecule activators of cardiac progenitor cell proliferation may form part of regenerative therapies for the treatment of myocardial infarction.

Extracellular Vesicles: The Driving Force Behind Cardiac Progenitor Cell Therapy

A study reports that extracellular vesicles from transplanted human cardiac progenitor cells drive the regenerative response following myocardial infarction

Predicting CPC Exosome Function with PLSR

Exosomes derived from cardiac progenitor cells (CPCs) can aid recovery from the severe right ventricular heart failure associated with congenital heart disease. In a recent STEM CELLS Translational Medicine study, researchers from the lab of Michael E.

Cell Therapy Outcome Prediction

A new STEM CELLS Translational Medicine study from the laboratory of Andre Terzic (Mayo Clinic, Rochester, Minnesota, USA) sought to understand outcome predictors when using stem cells to treat heart failure.

Epigenetic Priming - The Key to Effective Stem Cell Therapies for the Injured Heart?

Epigenetic priming of pluripotent stem cell-derived cardiac progenitor cells with polyinosinic‐polycytidylic acid results in mature cardiomyocyte production

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