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Amniotic Stem Cells

Gestational Diabetes-induced Changes to Amniotic Membrane MSCs May Impact Offspring

Researchers establish that gestational diabetes mellitus can influence amniotic membrane stem cell function, providing a mechanism for how maternal metabolism affects offspring

Enhanced Large Animal Wound Healing with Amnion-based Therapeutics

Positive outcomes observed in a large animal model provide evidence for the translational value of amnion membrane-derived treatments for wound treatment

Fetal Precursor Cells in Gestational Diabetes

Research efforts have suggested that signatures of metabolic deregulation remain in cells early in development and, given their location on the inner side of the placenta, amniotic membrane stem cells may represent an indicator of how the intrauterine environment impacts the fetus.

Long-term Outcomes of hAECS for BPD

Previous research from the lab of Atul Malhotra (Monash University, Clayton, Victoria, Australia) reported on the immediate safety and neonat

A Step Towards the Treatment of Hematopoietic Disease with Amniotic Fluid Stem Cells

Researchers describes a means to expand HFSCs that engraft after intravascular administration in an autologous-like murine model of in-utero transplantation

In Utero hAFSCs Protect Spinal Cord from MMC

Researchers from the lab of Daigo Ochiai (Keio University School of Medicine, Tokyo, Japan) recently investigated the therapeutic effects and mechanisms of human amniotic fluid stem cell (hAFSC)‐based treatment for fetal myelomeningocele (MMC), due to its poor diagnosis and lack of prenatal treatments.

In Utero Transplantation of Amniotic Fluid Stem Cells

The in-utero transplantation of hematopoietic stem cells for the prenatal treatment of congenital hematological diseases suffers from sub‐therapeutic levels of long‐term hematopoietic engraftment.

Cell-Free Amniotic Membrane-derived Hydrogel Boosts Skin Wound Healing

By combining solubilized amniotic membrane into an easy to store and apply hydrogel, researchers have developed a cell-free means to accelerate wound healing

Identifying Stem Cell Factors which Repair the Heart

Researchers identify factors excreted from stem cells derived from the amniotic membrane of human placenta which aid cardiac repair.

Amniotic Fluid Stem Cells Aid Kidney Transplantation in Porcine Model

Mesenchymal stem cells derived from amniotic fluid are shown to protect against kidney fibrosis following transplantation in a pre-clinical model

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