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Amniotic Stem Cells

Cell Therapy Infusion in Neonates

A new article describes a protocol for the intravenous delivery of cell therapy in neonates 

Attenuate Astrogliosis in Preterm Fetal Sheep with hAECs

Human amnion epithelial cell treatment may inhibit the white matter maturational failure observed in preterm infants 

Neuroprotective Effects of hAFSC-derived Secretome

A new study reports on the potential of the human amniotic fluid stem cell (hAFSC) secretome as a therapeutic approach to ischemia/reperfusion injury

Amniotic MSCs Modulate B-cell Responses in the Lungs

While immunomodulation by amniotic cells can create a microenvironment that limits the evolution of chronic inflammation to fibrosis, the immune modulation induced by amniotic mesenchymal stem cells (AMSCs) in models of fibrosis remains unexplored.

Gestational Diabetes-induced Changes to Amniotic Membrane MSCs May Impact Offspring

Researchers establish that gestational diabetes mellitus can influence amniotic membrane stem cell function, providing a mechanism for how maternal metabolism affects offspring

Enhanced Large Animal Wound Healing with Amnion-based Therapeutics

Positive outcomes observed in a large animal model provide evidence for the translational value of amnion membrane-derived treatments for wound treatment

Fetal Precursor Cells in Gestational Diabetes

Research efforts have suggested that signatures of metabolic deregulation remain in cells early in development and, given their location on the inner side of the placenta, amniotic membrane stem cells may represent an indicator of how the intrauterine environment impacts the fetus.

Long-term Outcomes of hAECS for BPD

Previous research from the lab of Atul Malhotra (Monash University, Clayton, Victoria, Australia) reported on the immediate safety and neonat

A Step Towards the Treatment of Hematopoietic Disease with Amniotic Fluid Stem Cells

Researchers describes a means to expand HFSCs that engraft after intravascular administration in an autologous-like murine model of in-utero transplantation

In Utero hAFSCs Protect Spinal Cord from MMC

Researchers from the lab of Daigo Ochiai (Keio University School of Medicine, Tokyo, Japan) recently investigated the therapeutic effects and mechanisms of human amniotic fluid stem cell (hAFSC)‐based treatment for fetal myelomeningocele (MMC), due to its poor diagnosis and lack of prenatal treatments.

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