Cancer Stem Cells

Researchers demonstrate that epigenetic silencing of TAP genes in breast cancer stem cells play a crucial role in immune evasion mechanisms

A new three-dimensional in vitro model of liver tumorigenesis may provide an efficient means to study cancer development and create new and effective therapies.

A new study suggests that dedifferentiated mature melanocytes represent the cell of origin for melanoma, and not stem cells as previously thought

A new study into colorectal cancer suggests that targeting FBXW7 may increase the sensitivity of cancer stem cells to commonly employed chemotherapeutics

A new study describes how hypoxia induces stem-like characteristics in brain tumor cells through the modulation of the chromatin environment of pluripotency-associated genes   

A new study of multiple adult stem cell types points to new hypothesis concerning differing cancer prevalence rates

The generation of liver cancer stem cells permits the delineation of important controlling pathways and potentially druggable targets for the treatment of liver cancer

Researchers studying the heterogeneous nature of cancer stem cell-containing skin tumors may have discovered new therapeutic targets

Unbiased transcriptomic and proteomic analysis provides the rational for an efficient dual targeting strategy to eradicate leukemic stem cells

Research into glioblastoma multiforme brain tumors uncovers a potentially exciting new therapeutic target – myeloid-derived suppressor cells