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Haematopoetic Stem Cells

Getting Physical (and Chemical) to Enhance Platelet Production

Researchers boost platelet production from cord blood hematopoietic stem/progenitor cells using a defined 3D culture system

Overturning the Classical View of the Hematopoietic System

A new study shakes the hematopoietic foundations and reveals a new view of how blood is formed in mice.

Normal and Leukemic Stem Cells Fight for a Place to Call Home

A new study demonstrates that normal and leukemic blood stem cells fight for the same niche with consequences for cancer treatment and transplantation.

A New Route for Stem Cell-based Cardiac Disease Therapy

The results of a new trial demonstrate an improved method to deliver stem cells to the failing heart.

De-stressing Stem Cells May Improve Clinical Utility

In a boost to transplantation based therapies, a new study finds that the application of a widely used immunosuppressant drug can inhibit the loss of stem cell functionality caused by the ambient oxygen concentrations encountered during bone marrow harvesting.

Stressed out HSCs Wake Up to DNA Damage

Researchers link physiological stress to HSC activation, increased DNA damage, and cell and tissue dysfunction.

First Successful Therapy for Multiple Sclerosis: Stem Cells Lead the Way

Hematopoietic stem cell transplantation improves clinical outcomes in multiple sclerosis; the first evidence of a successful treatment for this disease.

Building Beyond Berlin - Effective Stem Cell HIV Treatment

Researchers experimentally mimic the “Berlin patient” by creating an HIV-resistant selectable stem cell population which can reconstitute the mouse hematopoietic system and resist HIV infection

Nanotubes from Stem Cell Progeny Help to Correct Storage Disorder

Hematopoietic stem cells differentiate into macrophages and correct a lysosomal storage disorder through nanotube-mediated lysosomal exchange

Autologous Hematopoietic Cell Therapy for Stroke Assessed in Humans

Early intervention with autologous blood stem/progenitor cells shows promise in promoting functional recovery and reduces lesion volume after ischemic stroke


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