Haematopoetic Stem Cells

A new study establishes that the m6A modification helps to regulate the symmetric commitment of hematopoietic stem cells by controlling Myc mRNA stability

Given that metabolism controls stem cell function and that purine metabolism represents a critical component of cellular metabolism, researchers from the laboratory of Hartmut Geiger

A new study suggests that CD166 interactions activate critical molecular pathways involved in enhancing hematopoietic stem/progenitor cell functions

A previous study out of the labs of Hal E.

Researchers describe how transcription factor cooperation aids the generation of hemogenic precursors from human fibroblasts via an endothelial intermediate

A report now establishes that intestinal graft-resident HSPCs contribute to long-term multilineage blood chimerism after human intestinal transplantation

A Cas9 variant with cell cycle-specific activity coupled with cell synchronization improves the efficiency of hematopoietic stem cell gene editing

A simple combination of two markers may provide a quick and easy means to sort mouse hematopoietic stem cell from blood samples

A study highlights an efficient means to expand hematopoietic stem/progenitor cells in non-enriched umbilical cord blood thereby boosting clinical potential

Researchers discover that treatment with microvesicles from young MSCs can rejuvenate aged HSCs and potentially improve bone marrow transplantation outcomes