Haematopoetic Stem Cells

A transcriptional comparison of hematopoietic stem cell niches identifies PGI2 as an endosteal bone marrow-associated factor that functions at cell-intrinsic and cell-extrinsic levels

High glucose levels epigenetically prime HSCs and macrophages to support the persistence of diabetes-related macrovascular complications

A new study describes the first case of G-CSF-mobilized autologous CD34-positive cell transplantation as a treatment for acute kidney injury

The cardiopoietic stem cell secretome confers a therapeutic molecular imprint on recipient hearts, while predictive systems profiling could inform on therapeutic responses

A new study uses somatic mutations and single-cell analysis to describe the unknowns of human development

A new study suggests that the rejuvenation of the hematopoietic system must take hematopoietic stem cells and the stem cell niche into account

Researchers report their discovery of prostacyclin as a novel hematopoietic stem cell regulator enriched in endosteal bone marrow niches

Researchers establish hematopoietic stem cell transplantation as a potentially exciting therapy bone repair in osteogenesis imperfecta

Glucose oxidase promotes peripheral mobilization of hematopoietic stem/progenitor cells that maintain their function in conditioned recipients

Targeting chaperone-mediated autophagy may represent an exciting means to enhance HSC function during the normal aging process or after stem cell transplantation