Haematopoetic Stem Cells

A Cas9 variant with cell cycle-specific activity coupled with cell synchronization improves the efficiency of hematopoietic stem cell gene editing

A simple combination of two markers may provide a quick and easy means to sort mouse hematopoietic stem cell from blood samples

A study highlights an efficient means to expand hematopoietic stem/progenitor cells in non-enriched umbilical cord blood thereby boosting clinical potential

Researchers discover that treatment with microvesicles from young MSCs can rejuvenate aged HSCs and potentially improve bone marrow transplantation outcomes

Researchers employ single cell analyses to describe the very earliest stages of the hematopoietic differentiation of human pluripotent stem cells

Researchers investigate the role of the Smarca5 chromatin remodelling factor in hematopoiesis using a new conditional knockout animal model

RNA-based analysis suggests the existence of additional blood immune cells not identified by the expression of surface markers or morphology

A new study now indicates that the lungs contain hematopoietic progenitors and contribute significantly to platelet formation 

Studies into the role of the non-canonical NF-κB signaling pathway provide unexpected findings and new insight into the regulation of the hematopoiesis and bone marrow failure

A new study demonstrates how reactive oxygen species can disrupt the differentiation of hematopoietic stem cells from pluripotent stem cells