Haematopoetic Stem Cells

A review discusses how studies of primary immunodeficiencies can widen our understanding of lymphopoiesis

A nanoparticle carrying siRNAs targeting the endothelial cells of the hematopoietic niche can alter stem/progenitor cell behavior and systemic leukocyte supply

Sirolimus administration might represent a clinically-relevant means to treat/prevent hematopoietic injury

Researchers report that the leptomeningeal barrier of the brain is continuously patrolled by bone marrow-derived progenitors

IRF7 deficiency enhances regeneration of hematopoietic stem and progenitor cells (HSPCs) under conditions of stress

Researchers have employed an engineered mouse model to fully explore the role of Separase in hematopoiesis and the function of hematopoietic stem cells

A new review links researchers and clinicians by discussing the implications of recent HSC research in model organisms

Hematopoietic stem cell culture in conditions that mimics the thymic niche enhances T lymphocyte progenitor cell production and maturation in thymic organoids

The processing of cord blood under lower-than-normal temperatures enhances the numbers of phenotypically and functionally defined self‐renewing HSCs

A new study reports a novel role for the cohesin protease, Separase, in hematopoiesis and hematopoietic stem cell function