Muscle Stem Cells

Aging negatively impacts muscle regeneration through altered metabolism, chromatin, transcription factor binding, and gene expression in muscle stem cells

New research explores the modulation of the immune system following the transplantation of muscle stem cells into a mouse model of inflammatory bowel disease

Inflammatory macrophages can promote the expansion of activated muscle stem cells during tissue repair by retaining cells in a proliferative and undifferentiated state.

A new study published in STEM CELLS Translational Medicine

The lack of dystrophin in muscle myofibers represents the central cause of Duchenne muscular dystrophy (DMD), the most common inherited muscular dystrophy; however, evidence suggests that DMD may also be a stem cell disease.

The construction of an engineered diaphragmatic muscle construct may represent a promising tool toward clinical applications in diaphragmatic regeneration

A new study highlights the vital role of immune cells in the generation of functional three-dimensional tissue-engineered muscle constructs

Muscle stem cell regulation by the FoxM1 transcription factor functions through the regulation of the Snhg8 and Gm26917 long non-coding RNAs

Researchers discover that the inhibition of a lysine methyltransferase allows for the long-culture and amplification of human muscle stem cells

A new STEM CELLS study describes how two members of the regeneration-associated Notch signaling pathway combine to coordinate muscle stem cell regulation