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Muscle Stem Cells

Dystrophin Restoration in Muscle Progenitor Cells

The lack of dystrophin in muscle myofibers represents the central cause of Duchenne muscular dystrophy (DMD), the most common inherited muscular dystrophy; however, evidence suggests that DMD may also be a stem cell disease.

A Step Towards Diaphragmatic Regeneration with Engineered Muscle Constructs

The construction of an engineered diaphragmatic muscle construct may represent a promising tool toward clinical applications in diaphragmatic regeneration

Macrophages: The Missing Ingredient of Functional 3D Tissue-engineered Muscle Constructs?

A new study highlights the vital role of immune cells in the generation of functional three-dimensional tissue-engineered muscle constructs

FoxM1 Regulates Muscle Stem Cell Proliferation and Survival via long non-coding RNAs

Muscle stem cell regulation by the FoxM1 transcription factor functions through the regulation of the Snhg8 and Gm26917 long non-coding RNAs

Setd7 Inhibition: The Way Forward for MuSC-based Therapies for Muscular Dystrophy?

Researchers discover that the inhibition of a lysine methyltransferase allows for the long-culture and amplification of human muscle stem cells

Researchers Discover how Notch Duo Coordinate Muscle Stem Cell Regulation

A new STEM CELLS study describes how two members of the regeneration-associated Notch signaling pathway combine to coordinate muscle stem cell regulation

New Muscle Stem Cell Expansion Technique May Boost Muscle Regeneration Strategies

A new soft fibrin culture substrate permits the selective expansion of muscle stem cells from bulk muscle tissue

Magnetic Sorting Promotes Clinical Applicability of Smooth Muscle Progenitor Cells

A new study describing the magnetic sorting of smooth muscle progenitor cells derived from human induced pluripotent stem cells may promote their clinical application

Investigating the Intracellular Regulators of Muscle Stem Cells

A new study describes the importance of the KLF7 transcription factor in the regulation of muscle stem cell activity

Reversing Muscle Stem Cell Aging with pro-IGF-II?

New research finds that a post-translationally processed isoform of IGF-II may be able to promote muscle regeneration in the elderly by modulating the muscle stem cell microenvironment


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