Muscle Stem Cells

Inflammatory macrophages can promote the expansion of activated muscle stem cells during tissue repair by retaining cells in a proliferative and undifferentiated state.

A new study published in STEM CELLS Translational Medicine

The lack of dystrophin in muscle myofibers represents the central cause of Duchenne muscular dystrophy (DMD), the most common inherited muscular dystrophy; however, evidence suggests that DMD may also be a stem cell disease.

The construction of an engineered diaphragmatic muscle construct may represent a promising tool toward clinical applications in diaphragmatic regeneration

A new study highlights the vital role of immune cells in the generation of functional three-dimensional tissue-engineered muscle constructs

Muscle stem cell regulation by the FoxM1 transcription factor functions through the regulation of the Snhg8 and Gm26917 long non-coding RNAs

Researchers discover that the inhibition of a lysine methyltransferase allows for the long-culture and amplification of human muscle stem cells

A new STEM CELLS study describes how two members of the regeneration-associated Notch signaling pathway combine to coordinate muscle stem cell regulation

A new soft fibrin culture substrate permits the selective expansion of muscle stem cells from bulk muscle tissue

A new study describing the magnetic sorting of smooth muscle progenitor cells derived from human induced pluripotent stem cells may promote their clinical application