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Mesenchymal Stem Cells

Origin and Adhesive Behavior of MSCs may Influence their Therapeutic Application

The site of origin of mesenchymal stem cells and their inherent adhesive capabilities may significantly influence their therapeutic application

Mesenchymal Stem Cell-based Combinatorial Treatment Shows Promise for Lung Repair

New research suggests that a combination of MSCs and ATRA treatment in the presence of p70S6k1 signaling can enhance lung repair in a mouse emphysema model

Induced Mesenchymal Stem Cells: A Promising New Treatment Strategy for Inflammatory Bowel Disease?

New research suggests that MSCs derived from induced pluripotent stem cells are as effective as adipose-derived MSCs in treating inflammatory bowel disease in mice

AKT-mTOR Signaling: The Key to Enhanced Tendon Differentiation of MSCs?

New research suggests that potentiating the AKT-mTOR signaling axis can boost tenogenesis of mesenchymal stem cells and improve current tendon repair strategies

Understanding Immunomodulation by MSCs: Follow that Monocyte!

New research demonstrates that immune cells help to mediate, distribute, and transfer the immunomodulatory effects of mesenchymal stem cells following systemic administration

Fungal Metabolite Boosts ASC Osteogenesis and Skeletal Regenerative Strategies

Researchers discover that an actin-cytoskeleton modifying fungal metabolite can promote the osteogenesis of adipose stem cells via an epigenetic mechanism

Promoting Mesenchymal Stem Cell Function with Survivin

A new study describes the role of the inhibitor-of-apoptosis protein family member Survivin in the survival and function of mesenchymal stem cells

MSC-derived Extracellular Vesicles Battle Inflammation with Inflammation!

New research demonstrates how proinflammatory stimuli can promote the production of extracellular vesicles from MSCs with enhanced immunomodulatory capacity.

Bone Marrow MSCs Defeat ASCs in an Osteogenic Face-Off

A study compares the in vivo osteogenic potential of mesenchymal stem cells and adipose-derived stem cells in the hope of creating efficient bone repair strategies

Extracellular Vesicles: A New Means to Rescue HSCs from the Effects of Irradiation

Researchers discover that extracellular vesicles derived from MSCs rescue HSCs from the effects of irradiation and may represent a new therapeutic option


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