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Mesenchymal Stem Cells

Optimized Three-dimensional Microgels Boost the Therapeutic Potential of MSCs

Altered stiffness during microgel-mediated preconditioning of MSCs can significantly improve therapeutic angiogenesis in a severe rodent model of critical limb ischemia

Magnetic Targeting of MSCs Improves Treatment of Lung Disease

Magnetic targeting of mesenchymal stem cells to the lungs of a silicosis mouse model provides for significantly enhanced therapeutic outcomes

MSC-EVS in Hematopoietic Engraftment

A recent review article summarizes findings from in vitro studies and preclinical models regarding the potential of MSC‐EVs in the improvement of hematopoietic function

AAT-MSCs Improves Innate Properties of MSCs

Alpha‐1 antitrypsin (AAT)‐overexpressing MSCs display improved intrinsic properties and sustained efficacy in the prevention of type 1 diabetes onset

Topical Stem Cell Therapies for the Ocular Surface

A review focuses on the potential of engineered MSC therapies that can be topically applied to the ocular surface to treat inflammatory disorders

Deciphering the Influence of B Cells in MSC Therapy for Fibrosis

The modulation of B cell responses by mesenchymal stem cell therapy can blunt inflammatory responses in the lung and reduce progression to fibrosis

MSC-derived Exosomal miRNA as a Novel Therapy for Fertility-impacting Condition?

Research reveals a critical role for exosomal miR‐17‐5P and SIRT7 in the treatment of premature ovarian insufficiency by human umbilical cord-derived MSC transplantation

Mesenchymal Stem Cells for Urinary Incontinence

A new study establishes the intraurethral application of adipose tissue stem cells as a safe and feasible means to treat urinary incontinence

Tissue Engineering and Regenerative Medicine for COVID‐19

A new Perspective highlights the impact of the recent COVID-19 pandemic on the present and future of tissue engineering and regenerative medicine research and therapies

GSTT1 – The Key to The Widespread Therapeutic Application of Human Mesenchymal Stem Cells?

Researchers identify the loss of glutathione S‐transferase theta 1 gene as a novel genomic DNA biomarker for human mesenchymal stem cell scalability

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