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Mesenchymal Stem Cells

Understanding Immunomodulation by MSCs: Follow that Monocyte!

New research demonstrates that immune cells help to mediate, distribute, and transfer the immunomodulatory effects of mesenchymal stem cells following systemic administration

Fungal Metabolite Boosts ASC Osteogenesis and Skeletal Regenerative Strategies

Researchers discover that an actin-cytoskeleton modifying fungal metabolite can promote the osteogenesis of adipose stem cells via an epigenetic mechanism

Promoting Mesenchymal Stem Cell Function with Survivin

A new study describes the role of the inhibitor-of-apoptosis protein family member Survivin in the survival and function of mesenchymal stem cells

MSC-derived Extracellular Vesicles Battle Inflammation with Inflammation!

New research demonstrates how proinflammatory stimuli can promote the production of extracellular vesicles from MSCs with enhanced immunomodulatory capacity.

Bone Marrow MSCs Defeat ASCs in an Osteogenic Face-Off

A study compares the in vivo osteogenic potential of mesenchymal stem cells and adipose-derived stem cells in the hope of creating efficient bone repair strategies

Extracellular Vesicles: A New Means to Rescue HSCs from the Effects of Irradiation

Researchers discover that extracellular vesicles derived from MSCs rescue HSCs from the effects of irradiation and may represent a new therapeutic option

Cell Volume modulates Mesenchymal Stem Cell Fate

Researchers studying microenvironmental influences on cell mechanics highlight a link between changes in cell volume and the differentiation potential of mesenchymal stem cells


Enhancing Cartilage Repair Strategies with ROR2

New research suggests that selecting MSCs based on inducible receptor tyrosine kinase-like orphan receptor 2 expression may lead to enhanced cartilage repair strategies

Organ-Specific “Tissue Papers” Created from Extracellular Matrix Ink

Researchers have developed a new means to utilize decellularized extracellular matrix in regenerative strategies including the maintenance of ovarian tissue 

Enhanced Bone Fracture Healing with Engineered Mesenchymal Stem Cells

The overexpression of basic fibroblast growth factor boosts bone fracture healing capacity of mesenchymal stem cells via the secretion of paracrine-acting factors


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