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Mesenchymal Stem Cells

Reduced Stress Responses: A Potential Problem for Autologous MSC-based Treatment of Multiple Sclerosis

Analyses of mesenchymal stem cells derived from MS patients suggests that lowered stress responses may inhibit therapeutic outcomes

Improving Mesenchymal Stem Cell Migration to the Damaged Lung Boosts Therapeutic Effects

Researchers discover that the overexpression of an Angiotensin II receptor in MSCs improves their migration to the injured lung and improves therapeutic effect

Clotting: An Added Consideration for Intravenous Infusion of Stem Cell Therapies?

Researchers establish that clinically relevant adult stem cell populations promote clot formation via the varying expression of the tissue factor clotting component

Resveratrol Battles Inflammation and Provides a Stem Cell Boost for Periodontal Repair

Researchers report that resveratrol can reverse inflammation-mediated effects, promote cell aggregation, and enhance stem cell-mediated periodontal repair

Origin and Adhesive Behavior of MSCs may Influence their Therapeutic Application

The site of origin of mesenchymal stem cells and their inherent adhesive capabilities may significantly influence their therapeutic application

Mesenchymal Stem Cell-based Combinatorial Treatment Shows Promise for Lung Repair

New research suggests that a combination of MSCs and ATRA treatment in the presence of p70S6k1 signaling can enhance lung repair in a mouse emphysema model

Induced Mesenchymal Stem Cells: A Promising New Treatment Strategy for Inflammatory Bowel Disease?

New research suggests that MSCs derived from induced pluripotent stem cells are as effective as adipose-derived MSCs in treating inflammatory bowel disease in mice

AKT-mTOR Signaling: The Key to Enhanced Tendon Differentiation of MSCs?

New research suggests that potentiating the AKT-mTOR signaling axis can boost tenogenesis of mesenchymal stem cells and improve current tendon repair strategies

Understanding Immunomodulation by MSCs: Follow that Monocyte!

New research demonstrates that immune cells help to mediate, distribute, and transfer the immunomodulatory effects of mesenchymal stem cells following systemic administration

Fungal Metabolite Boosts ASC Osteogenesis and Skeletal Regenerative Strategies

Researchers discover that an actin-cytoskeleton modifying fungal metabolite can promote the osteogenesis of adipose stem cells via an epigenetic mechanism

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