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Mesenchymal Stem Cells

Preclinical MSC-Exosomes: A Review

The growing interest surrounding the therapeutic application of purified and concentrated regenerative factors secreted by mesenchymal stem cell (MSCs) has recently focused on exosomes, which are now understood to be critical active pharmaceutical ingredients of MSC‐based therapies.

Micronized Fat Versus BMAC for Knee Osteoarthritis

A recent STEM CELLS Translational Medicine article from the lab of Robert Bowers (Emory University, Atlanta, Georgia, USA) ai

TNTs Mediate Senescence in MSC Spheroids

Previous studies from the labs of J.

Challenges for MSCs in the Clinic

The realization that mesenchymal stem cells (MSCs) play tissue supportive functions has prompted an increasing number of studies in a variety of clinical indications, thereby revealing additional challenges.

Tonsil-derived MSCs in Tissue Regeneration

A recent concise review article in STEM CELLS from the laboratory of Inho Jo (Ewha Womans University, Seoul, Republic of Korea) summarizes the differentiation capacities of tonsil‐derived mesenchymal stem cells (MSCs) and their therapeutic competencies. Oh et al.

Stem Cell Extracellular Vesicles Mediate Corneal Regeneration

Researchers led by James L. Funderburgh (University of Pittsburgh, Pittsburgh, Pennsylvania, USA) recently sought to understand the mechanisms by which corneal stromal stem cells enhance corneal wounding by assessing extracellular vesicles.

Mesenchymal Stromal Cells Anno 2019

A recently published Concise Review from Martin J.

Carbon Dot-mediated Inhibition of Inflammation Boosts Cartilage Regeneration by MSCs

A study appraises the potential of carbon dots as a replacement for quantum dots to transfect siRNA into MSCs to boost chondrogenic differentiation in vivo

Optimizing Atorvastatin-pretreated MSCs for AMI Treatment

Previous studies from the labs of Li Qian (University of North Carolina at Chapel Hill, USA) and

Cord Tissue MSCs Show Consistency Between Donors

Human umbilical cord tissue represents an excellent source of mesenchymal stem cells (MSCs), and a recent study from the lab of Ian Rogers (Sinai Health System, Toronto, Ontario, Canada) sought to fully characterize can compare cells derived from multiple donors. In their new STEM CELLS Translational Medicine study, Raileanu et al.

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