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Mesenchymal Stem Cells

Novel Huntington’s Disease Mouse Model of Neuroinflammation

The description of a novel immunodeficient mouse model of Huntington's disease may aid the development of therapeutic approaches

MSC Interactions with Vascular Endothelium in Stroke

Mitochondrial transfer highlighted as a therapeutic mechanism controlling the ability of MSC therapy to suppress excess inflammation

PLXDC2‐OT Promotes MSC Osteogenesis

The PLXDC2‐OT long non-coding RNA inhibits the RBM6-SIRT7 interaction to promote the osteogenic potential of mesenchymal stem cells

MSC Suppress Inflammation via ICOS‐ICOSL Interactions

A new study reveals the critical nature of ICOSL-induced T regulatory cells in the mesenchymal stem cell-mediated inhibition of group 2 innate lymphoid cells

SHEDs in T2D Treatment

The transplantation of stem cells from human exfoliated deciduous teeth may represent a simple, safe, and effective therapy for diabetic patients

Combined Cell Therapy as an Enhanced Treatment for Traumatic Brain Injury

A combined Treg and mesenchymal stem cell therapy significantly decreases systemic inflammation following traumatic brain injury

MSC‐mediated Immune Regulation in T2DM

A review discusses the plasticity and underlying mechanisms of MSC‐mediated immune modulation and explores the therapeutic potential of MSCs for T2DM treatment

Can FZD5 Boost the Therapeutic Relevance of Human Mesenchymal Stem Cells?

Frizzled 5 plays a crucial role in regulating the maintenance of proliferation and multilineage differentiation potential of human mesenchymal stem cells

Dermal MSCs as a RDEB Treatment

Study demonstrates that ABC5-expressing dermal MSCs have a superior skin-homing capacity when compared to bone marrow-derived MSCs

Lithium Preconditioning Boosts Stroke Treatment by MSC-derived Extracellular Vesicles

Treatment with extracellular vesicles derived from lithium-preconditioned MSCs prompts neuroprotection and neuroregeneration following experimental stroke

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