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Mesenchymal Stem Cells

ACE2 Expression in MSCs

MSCs derived from the placenta or iPSCs display the lowest levels of ACE2 expression and the best anti-inflammatory properties

SARS-CoV-2 Does Not Infect hMSCs

A new article establishes that human mesenchymal stem cells are not permissive to SARS‐CoV‐2 infection

Reprogramming Monocytes and Macrophages with MSCs

A new study describes the interactions controlling how macrophages engulf cytoplasmic components of MSCs and undergo transcriptional reprogramming

Lithium-treated Extracellular Vesicles Protect Against Stroke

EVs derived from lithium preconditioned MSCs possess enhanced therapeutic potential in the treatment of stroke

 

EEMs and Exosomes Promote Ligament Healing

EEMs reduce inflammation and improve ligament strength, while exosomes decrease scar size and increase collagen organization and production

Osteocyte-derived Extracellular Vesicles – A Novel Approach to Bone Regeneration?

Extracellular vesicles from mechanically stimulated osteocytes drive MSC recruitment and osteogenesis and may represent a cell-free bone regeneration strategy

MSC Biomarker Identification may Improve Osteoarthritis Therapies

The identification of biomarkers that correlate with chondrogenic potential and trophic repair during MSC aging may lead to improved osteoarthritis treatments

Sensory Nerves in the Stem Cell Niche

A new review summarizes progress in our understanding of the biology of sensory nerve function in stem cell niches

Engineered Cardiopoietic Stem Cell Therapy

A new article reports the engineering of cardiac repair competent stem cells using Brachyury, a mesodermal transcription factor

3D Porous Scaffolds for Early Bone Integration

New research reveals superior bone formation in bone marrow MSC‐laden composites in rat tibial defects

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