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Mesenchymal Stem Cells

Challenges for MSCs in the Clinic

The realization that mesenchymal stem cells (MSCs) play tissue supportive functions has prompted an increasing number of studies in a variety of clinical indications, thereby revealing additional challenges.

Tonsil-derived MSCs in Tissue Regeneration

A recent concise review article in STEM CELLS from the laboratory of Inho Jo (Ewha Womans University, Seoul, Republic of Korea) summarizes the differentiation capacities of tonsil‐derived mesenchymal stem cells (MSCs) and their therapeutic competencies. Oh et al.

Stem Cell Extracellular Vesicles Mediate Corneal Regeneration

Researchers led by James L. Funderburgh (University of Pittsburgh, Pittsburgh, Pennsylvania, USA) recently sought to understand the mechanisms by which corneal stromal stem cells enhance corneal wounding by assessing extracellular vesicles.

Mesenchymal Stromal Cells Anno 2019

A recently published Concise Review from Martin J.

Carbon Dot-mediated Inhibition of Inflammation Boosts Cartilage Regeneration by MSCs

A study appraises the potential of carbon dots as a replacement for quantum dots to transfect siRNA into MSCs to boost chondrogenic differentiation in vivo

Optimizing Atorvastatin-pretreated MSCs for AMI Treatment

Previous studies from the labs of Li Qian (University of North Carolina at Chapel Hill, USA) and

Cord Tissue MSCs Show Consistency Between Donors

Human umbilical cord tissue represents an excellent source of mesenchymal stem cells (MSCs), and a recent study from the lab of Ian Rogers (Sinai Health System, Toronto, Ontario, Canada) sought to fully characterize can compare cells derived from multiple donors. In their new STEM CELLS Translational Medicine study, Raileanu et al.

Improving Mesenchymal Stem Cell Therapies with TSG‐6

A new study demonstrating how TSG-6 regulates stemness and directs cellular functions in mouse MSCs may allow for improved outcomes in human MSC therapies

UC-MSC Treatment in Children with Autism Spectrum Disorder

Children with autism spectrum disorder (ASD) can suffer from immune dysregulation and inflammation, and now, a STEM CELLS Translational Medicine article from the lab of Neil H.

MSC Therapy for Acute Respiratory Distress Syndrome

A new STEM CELLS Translational Medicine article from the laboratory of

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