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Mesenchymal Stem Cells

Mesenchymal Stem Cells and Stimulated Macrophages: An Efficient Combination Treatment for Cirrhosis?

Researchers discover enhanced liver repair following treatment with mesenchymal stem cells and stimulated macrophages in a mouse model of cirrhosis

Single-cell Analysis Reveals the Impact of Aging on Mesenchymal Stem Cells

New research reports that young MSCs promote more rapid wound healing than old MSCs and uncovers single-cell age-related transcriptional differences

Novel Long non-coding RNA Regulates Osteogenesis of Bone Marrow Mesenchymal Stem Cells

Researchers discover a novel lncRNA linked to the osteogenesis of bone marrow MSCs and also describe the crucial interaction of this lncRNA with hnRNPK

Epigenetic Control of Bone Formation by Ash1l: A New Target for the Treatment of Bone Disorders?

Researchers describe how targeting the activity of a histone methyltransferase may lead to the development of improved therapies for common bone disorders

Metabolic Switch Supports Human Mesenchymal Stem Cell Immunosuppression

Researchers describe the metabolic alterations in MSCs following immune licensing that support the secretion of  key immunosuppressive factors

Serum-free Growth Media Improves Mesenchymal Stem Cell Therapy for Chronic Kidney Disease

Researchers searching for a therapy for kidney damage establish the advantages of cultivating mesenchymal stem cells in serum-free media prior to application

Trialing Mesenchymal Stem Cell Therapy as an Effective Approach for Sepsis Treatment

The results of a new human trial suggest that mesenchymal stem cell therapy may represent an effective means to treat the inflammation associated with sepsis

Micro‐fragmented Adipose Tissue: A Time Sparing and Cost‐Effective Treatment Strategy for Osteoarthritis?

New study highlights the exciting potential for autologous micro‐fragmented adipose tissue in the treatment of osteoarthritis in patients following an animal trial

Reduced Stress Responses: A Potential Problem for Autologous MSC-based Treatment of Multiple Sclerosis

Analyses of mesenchymal stem cells derived from MS patients suggests that lowered stress responses may inhibit therapeutic outcomes

Improving Mesenchymal Stem Cell Migration to the Damaged Lung Boosts Therapeutic Effects

Researchers discover that the overexpression of an Angiotensin II receptor in MSCs improves their migration to the injured lung and improves therapeutic effect

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