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Mesenchymal Stem Cells

UC-MSC Trial for COVID-19

A new trial reports that UC-MSC infusions are associated with higher survival rates in patients suffering from coronavirus disease 2019.

Cell-based Therapies in Diabetic Kidney Disease

Researchers quantitatively summarize the therapeutic effect and factors influencing regenerative, cell-based therapies in experimental diabetic kidney disease

Metabolic Disease Impacts MSC Efficacy

A new study reports the safety of autologous administration of bone marrow-derived mesenchymal stem cells in patients with type 2 diabetes mellitus

HMGA1 Aids the NFIX-mediated Osteogenesis of MSCs

A new study suggests NFIX/HMGA1 as a novel therapeutic target for treating metabolic bone disorders such as osteoporosis

Embryonic Progenitors in Spinal Development and Repair

Embryonic Col2+ cells contribute to spinal cord development while Col2+ progenitors participate in intervertebral disc repair and regeneration

MSC Therapy for Immune and Inflammatory Disease

A new review article provides an update and discusses the outcomes of current mesenchymal stem cell therapy trials for immune and inflammatory disease

miR‐351‐3p Promotes AFMSCs Proliferation

Early passage amniotic fluid‐derived mesenchymal stem cells display significantly higher proliferation than late-passage cells due to miR‐351‐3p expression

Bead-to-Bead Transfer for MSC Manufacturing

A bead-to-bead cell transfer process with intermittent agitation supports the scale-up of human mesenchymal stem cell culture in bioreactors

How Age and Injury Impact the Mesenchyme

Researchers analyze the expression of mesenchymal markers in young and old mice following unilateral ischemia-reperfusion injury

Treating Mycobacterial Infections with MSCs

Researchers report the antimicrobial and anti‐inflammatory capacity of MSCs when facing Mycobacterium infections and highlight donor-related potency

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