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Mesenchymal Stem Cells

Metabolic Switch Supports Human Mesenchymal Stem Cell Immunosuppression

Researchers describe the metabolic alterations in MSCs following immune licensing that support the secretion of  key immunosuppressive factors

Serum-free Growth Media Improves Mesenchymal Stem Cell Therapy for Chronic Kidney Disease

Researchers searching for a therapy for kidney damage establish the advantages of cultivating mesenchymal stem cells in serum-free media prior to application

Trialing Mesenchymal Stem Cell Therapy as an Effective Approach for Sepsis Treatment

The results of a new human trial suggest that mesenchymal stem cell therapy may represent an effective means to treat the inflammation associated with sepsis

Micro‐fragmented Adipose Tissue: A Time Sparing and Cost‐Effective Treatment Strategy for Osteoarthritis?

New study highlights the exciting potential for autologous micro‐fragmented adipose tissue in the treatment of osteoarthritis in patients following an animal trial

Reduced Stress Responses: A Potential Problem for Autologous MSC-based Treatment of Multiple Sclerosis

Analyses of mesenchymal stem cells derived from MS patients suggests that lowered stress responses may inhibit therapeutic outcomes

Improving Mesenchymal Stem Cell Migration to the Damaged Lung Boosts Therapeutic Effects

Researchers discover that the overexpression of an Angiotensin II receptor in MSCs improves their migration to the injured lung and improves therapeutic effect

Clotting: An Added Consideration for Intravenous Infusion of Stem Cell Therapies?

Researchers establish that clinically relevant adult stem cell populations promote clot formation via the varying expression of the tissue factor clotting component

Resveratrol Battles Inflammation and Provides a Stem Cell Boost for Periodontal Repair

Researchers report that resveratrol can reverse inflammation-mediated effects, promote cell aggregation, and enhance stem cell-mediated periodontal repair

Origin and Adhesive Behavior of MSCs may Influence their Therapeutic Application

The site of origin of mesenchymal stem cells and their inherent adhesive capabilities may significantly influence their therapeutic application

Mesenchymal Stem Cell-based Combinatorial Treatment Shows Promise for Lung Repair

New research suggests that a combination of MSCs and ATRA treatment in the presence of p70S6k1 signaling can enhance lung repair in a mouse emphysema model

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