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Mesenchymal Stem Cells

The Abca4/miR-351-3p – The Key to Therapeutic Success in Amniotic Fluid MSCs?

Modulating the Abca4/miR-351-3p axis may generate amniotic fluid-derived mesenchymal stem cells suited to regenerative medicine applications 

MSC Treatment of COPD

The results of a new trial provide novel insights that may guide the development of MSC therapy as a treatment option for patients with chronic airway diseases

Single Cell Analysis of MSC Osteogenesis

Analysis of chemically induced osteogenesis in human adipose-derived mesenchymal stem cells via single-cell RNA-sequencing

Safe MSC Therapy for Chronic Knee Pain

Mesenchymal stem cells with trisomy seven were comparable to cells without trisomy seven from a safety perspective

Reviewing Allogeneic MSCs for Cartilage Regeneration

A new review summarizes the potential of allogeneic mesenchymal stem cell-based therapies for articular cartilage repair

Human MSC Therapy – An Efficient Alternative Treatment for Mycobacterial Infections?

Human mesenchymal stem cell administration may represent a safe and efficient alternative therapeutic strategy for chronic infections of hard-to-treat bacteria 

Phase II Trial Suggests Safety and Feasibility of MSC Therapy for Chronic Lung Disease in Preterm Infants

A clinical trial assesses the therapeutic efficacy of human umbilical cord blood‐derived MSC transplantation for bronchopulmonary dysplasia in preterm infants

UC-MSCs in Muscular Dystrophy Treatment

Treatment of patients with muscular dystrophies with an advanced therapy medicinal product containing umbilical cord-derived mesenchymal stem cells

DUSP5 Promotes MSC Osteogenesis

DUSP5 promotes the osteoblastic differentiation of MSCs by activating SMAD1 signaling in an SCP1/2 dependent manner

Stem Cell Therapeutics for Frailty

A new review article summarizes our current understanding of frailty from processes mediated by inflammation, aging, and stem cells

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