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Mesenchymal Stem Cells

Wntless Deletion in Aging Bone Marrow Stem Cells

Osteoblastic Wls deletion impairs the bone marrow microenvironment and bone mass accrual, while also inducing age‐independent senescence of MSCs

Optimized Three-dimensional Microgels Boost the Therapeutic Potential of MSCs

Altered stiffness during microgel-mediated preconditioning of MSCs can significantly improve therapeutic angiogenesis in a severe rodent model of critical limb ischemia

Magnetic Targeting of MSCs Improves Treatment of Lung Disease

Magnetic targeting of mesenchymal stem cells to the lungs of a silicosis mouse model provides for significantly enhanced therapeutic outcomes

MSC-EVS in Hematopoietic Engraftment

A recent review article summarizes findings from in vitro studies and preclinical models regarding the potential of MSC‐EVs in the improvement of hematopoietic function

AAT-MSCs Improves Innate Properties of MSCs

Alpha‐1 antitrypsin (AAT)‐overexpressing MSCs display improved intrinsic properties and sustained efficacy in the prevention of type 1 diabetes onset

Topical Stem Cell Therapies for the Ocular Surface

A review focuses on the potential of engineered MSC therapies that can be topically applied to the ocular surface to treat inflammatory disorders

Deciphering the Influence of B Cells in MSC Therapy for Fibrosis

The modulation of B cell responses by mesenchymal stem cell therapy can blunt inflammatory responses in the lung and reduce progression to fibrosis

MSC-derived Exosomal miRNA as a Novel Therapy for Fertility-impacting Condition?

Research reveals a critical role for exosomal miR‐17‐5P and SIRT7 in the treatment of premature ovarian insufficiency by human umbilical cord-derived MSC transplantation

Mesenchymal Stem Cells for Urinary Incontinence

A new study establishes the intraurethral application of adipose tissue stem cells as a safe and feasible means to treat urinary incontinence

Tissue Engineering and Regenerative Medicine for COVID‐19

A new Perspective highlights the impact of the recent COVID-19 pandemic on the present and future of tissue engineering and regenerative medicine research and therapies

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