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Mesenchymal Stem Cells

MSCs and 3D Scaffold Regenerate Bone Defects

New mesenchymal stem cell-based approaches support the regeneration of high‐quality bone in a critical-size defect in a swine model

Macrophages at the Nexus of MSC Potency

A new review examines the effect of culture‐adapted mesenchymal stem cells on macrophage polarization and their clinical utility

Increased Immunomodulation by Aggregated MSCs

Researchers describe the development of a bioengineered platform enabling the systematic control of aggregate size and aggregation kinetics

MSCs Relevant for ARDS Therapy Display Resistance to SARS‐CoV‐2 Infection

A new study defines the ACE2 and TMPRSS2 expression profile in human MSCs of adult and fetal origin and explores their permissivity to SARS‐CoV‐2 infection

Using the Power of the Nuclear Piston to Drive MSC Migration!

The stiff nature of the nucleus contributes to mesenchymal stem cells migration through confining and viscoelastic matrices by generating migration paths

Intra-bone Mesenchymal Stem Cell Injection Boosts Cord Blood Transplant in Adults

Cotransplantation of mesenchymal stem cells may prevent graft‐vs‐host disease in adult human patients without negatively impacting cord blood engraftment

Human Induced Multipotent Stem Cells: A Novel Alternative for Tissue-regeneration Strategies

Further improvements to a protocol for converting human adipocytes into induced multipotent stem cells may lead to the development of enhanced tissue-regeneration strategies

MSC Therapy for Diabetes-related Kidney Injury

New research highlights mitochondrial transfer from MSCs to macrophages as a means to restrict inflammation and alleviate kidney injury in diabetic nephropathy mice

Novel Huntington’s Disease Mouse Model of Neuroinflammation

The description of a novel immunodeficient mouse model of Huntington's disease may aid the development of therapeutic approaches

MSC Interactions with Vascular Endothelium in Stroke

Mitochondrial transfer highlighted as a therapeutic mechanism controlling the ability of MSC therapy to suppress excess inflammation

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