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Neural Stem Cells

Human Ventral Forebrain Neural Stem Cells

Intraventricular hemorrhage (IVH) occurs in 15% to 40% of preterm births and is frequently associated with long‐term neurological deficits. The rupture of the proliferative germinal zone following IVH disturbs the late production of neurons, ependymal cells, and glial cells.

Norepinephrine Negatively Regulates the NSC Niche

Various factors, including growth factors and neurotransmitters such as dopamine, regulate adult neurogenesis.

Galectin‐3 Inhibits Wnt Signaling in the pSVZ

The pro‐inflammatory molecule Galectin‐3 (Gal‐3), which is frequently increased in cancer and injury, regulates inflammation and subventricular zone (SVZ) neurogenesis; however, the signaling pathways involved remain poorly understood.

Clinical Grade hNSCs Rescue HD-associated Deficits

In a new STEM CELLS study, researchers led by

ZnT3 Maintains Adult Hippocampal Neurogenesis

Researchers led by Sang Won Suh (Hallym University, Chuncheon, South Korea) recently evaluated the hypothesis that the Zinc transporter 3 (ZnT3) protein and

DRD1 - A New Target in the Battle Against the Age-related Decline in Neurogenesis?

The discovery that DRD1 activity regulates neurogenesis during human brain development may provide a means to counter the loss of neural stem cell activity associated with aging

Vimentin Helps to Keep Proteins in Balance in Neural Stem Cells

A new study explores the complex responses of neural stem cells to elevated levels of damaged proteins to highlight mechanisms that could enhance adult neurogenesis

Stroke‐induced Neurogenesis by lncRNAs

Adult neurogenesis contributes to neurological function; therefore, elucidating the underlying molecular mechanisms in post‐stroke neurogenesis could provide for the development of new therapies to amplify endogenous neurogenesis and improve neurological function during recovery.

Deciphering the microRNA-mediated Control of Neural Stem Cell Function

Researchers establish that the miR‐137 microRNA modulates human neural stem cell fate by influencing mitochondrial dynamics through a number of mechanisms

BMP Regulates Id1 Mediated NSC Quiescence

The tight control of neural stem cells (NSCs) quiescence and proliferation helps to maintain the supply of new neurons and avoid the exhaustion of the NSC pool.


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