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Neural Stem Cells

Norepinephrine - A New Niche-specific Regulator of Adult Neurogenesis

The neurotransmitter norepinephrine functions as a regulator of adult neural progenitor cell proliferation within the periventricular regions of the adult mouse brain

MRI Tracking of Intracranial Stem Cell Grafts

Magneto‐endosymbionts may represent an effective tool for the in vivo monitoring of cell‐based therapies with potential relevance to neurological applications

NSCs Isolated from Preterm Infants May Pave the Way to New Treatment Strategies

Neural stem cells isolated from preterm infants may prompt the development of novel therapies that restore neurogliogenesis and attenuate neurocognitive deficits

Transplantation of Clinical Grade NSCs Shows Potential as a Huntington's Disease Treatment

Implantation of NSCs in a Huntington's disease model significantly improves behavior and pathology via cell replacement and the induction of host cell regeneration

Rapid Induction of Gliogenesis in Spheroids

Researchers now describe the culture of 3D cerebral organoids that rapidly generate astrocytes and oligodendrocytes and recapitulate the developing human brain

Long Non-coding RNAs – The Key to Functional Recovery from Stroke?

The H19 lncRNA mediates stroke‐augmented neurogenesis in neural stem cells through a mechanism involving chromatin remodeling proteins

Deciphering the Molecular Mechanisms Controlling Spinal Cord Regeneration

Injury shifts the regenerating corticospinal motor neuron transcriptome towards an immature state, with the huntingtin gene acting as a central transcriptomic hub

Human Ventral Forebrain Neural Stem Cells

Intraventricular hemorrhage (IVH) occurs in 15% to 40% of preterm births and is frequently associated with long‐term neurological deficits. The rupture of the proliferative germinal zone following IVH disturbs the late production of neurons, ependymal cells, and glial cells.

Norepinephrine Negatively Regulates the NSC Niche

Various factors, including growth factors and neurotransmitters such as dopamine, regulate adult neurogenesis.

Galectin‐3 Inhibits Wnt Signaling in the pSVZ

The pro‐inflammatory molecule Galectin‐3 (Gal‐3), which is frequently increased in cancer and injury, regulates inflammation and subventricular zone (SVZ) neurogenesis; however, the signaling pathways involved remain poorly understood.

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