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Adipose Stem Cells

Collagenase-free Methods for Tissue SVF Isolation

The tissue stromal vascular fraction of adipose tissue, a heterogeneous cell population containing adipose‐derived stem cells, has been successfully applied in translational studies and clinical trials.

MSC Properties Rely on Tissue of Origin

Researchers led by Karin Tarte (Université de Rennes, France) recently assessed the influence of tissue of origin on the functional properties of mesenchymal stem cells (MSCs) in a recent STEM CELLS study. Ménard et al.

Immunoregulatory Role of hASC-CCR7 in VCA

A new study from the laboratories of Yan Han and Hong Li (First Medical Centre of Chinese PLA General Hospital, Beijing, People's Republic of China) recently explored the utility of Chemokine receptor 7 (CCR7) overexpression in human adipose-derived stem cells (hASCs) as a means to induce immune intolerance following vascularized composite allotransplantation (VCA).

Reviewing Adipose Stem Cells and Cancer

The interaction of cancer cells with the multitude of other cell types present within the tumor microenvironment plays a crucial role in cancer development and progression.

ASCs Restore Bone Regeneration After Infection

Previous research from the lab of Björn Behr (University Hospital Bergmannsheil Bochu

Single MSC Injection Provides Functional improvements and Pain Relief for Knee Osteoarthritis Patients

Trial of intra‐articular injections of autologous adipose-derived MSCs in patients with knee osteoarthritis provides proof of functional improvement and pain relief

Boosting ASC-mediated Cardiac Regeneration by Statin-Polymer Nanoparticles

In the hope of developing more efficient stem cell-treatments for ischemic heart diseases, researchers led by Masaaki Ii (Osaka Medical College, Japan) recently assessed the outcomes of a combinatorial strategy on the ischemic myocardium. In brief, Yokoyama et al.

Comparing the Regenerative Potential of SVF and MFAT - Which Adipose Tissue Preparation Comes out Top?

A new study shows how adipose-tissue fragmentation preserves perivascular cell content and growth factor and cytokine secretion compared to enzymatic dissociation

Multipotent Adipose‐derived Stem Cells: A Novel Stem Cell Source for Functional Hepatocytes?

Researchers employing single-cell RNA seq report on the steps involved in the generation of functional hepatocyte-like cells from a novel stem cell source

Study of Adipose Stem Cells in Blind Mole Rats Hints at new Anti-tumor Strategy

A new study of the blind mole rat uncovers a link between adipose stem cell migration, intratumoral angiogenesis, and cancer resistance

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