Adipose Stem Cells

Bone regrowth may be achieved using different biomaterial scaffolds that provide structural and biological cues to stem cells to stimulate osteogenic differentiation. Furthermore, new knowledge regarding the mechanisms of bone repair is of paramount importance to address the significant steps required for precise translational medicine to treat patients.

Adipose‐derived mesenchymal stem cells (ASCs) are a valuable cell source for regenerative medicine, and prolonged in vitro cell expansion may be required to develop ASC‐based products.

Radiation therapy stimulates progressive and pathological soft tissue fibrosis, which distorts tissue form and negatively influences function. Researchers from the lab of Derrick C.

New research suggests that CCR7-overexpressing human ASCs possess a greater immunomodulatory capacity and enhance the survival of vascularized composite allotransplants

The tissue stromal vascular fraction of adipose tissue, a heterogeneous cell population containing adipose‐derived stem cells, has been successfully applied in translational studies and clinical trials.

Researchers led by Karin Tarte (Université de Rennes, France) recently assessed the influence of tissue of origin on the functional properties of mesenchymal stem cells (MSCs) in a recent STEM CELLS study. Ménard et al.

A new study from the laboratories of Yan Han and Hong Li (First Medical Centre of Chinese PLA General Hospital, Beijing, People's Republic of China) recently explored the utility of Chemokine receptor 7 (CCR7) overexpression in human adipose-derived stem cells (hASCs) as a means to induce immune intolerance following vascularized composite allotransplantation (VCA).

The interaction of cancer cells with the multitude of other cell types present within the tumor microenvironment plays a crucial role in cancer development and progression.

Previous research from the lab of Björn Behr (University Hospital Bergmannsheil Bochu

Trial of intra‐articular injections of autologous adipose-derived MSCs in patients with knee osteoarthritis provides proof of functional improvement and pain relief