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Understanding Metabolism to Improve MSC Survival

To develop the next generation of cell‐delivery materials and methods, we must have a better understanding of the metabolic switches mesenchymal stem cells (MSCs) experience upon transplantation. By designing treatment strategies with cell metabolism in mind, we may improve survival and the overall therapeutic potential of MSCs. Now, researchers from the laboratory of Hervé Petite provide a comprehensive review of plausible metabolic switches in response to implantation and the various strategies currently used to leverage MSC metabolism to improve stem cell‐based therapeutics. See STEM CELLS for more.