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Ultrasound for Enhancing MSC-based Therapies

Mesenchymal stem cells (MSCs) represent a popular platform for regenerative medicine due to their ability to home to damaged organs and secrete molecules that promote cell growth and suppress inflammation; however, there remains a need to optimize their therapeutic effect for clinical translation. A team of researchers led by Avnesh S. Thakor (Stanford University, Palo Alto, CA, USA) now reviews current knowledge regarding how ultrasound can enhance the ability of MSCs to secrete regenerative molecules or make target organs a more attractive destination for infused MSCs. See STEM CELLS Translational Medicine for the biological effects and preclinical applications of ultrasound to MSC‐based therapies.