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UC-MSC Treatment in Children with Autism Spectrum Disorder

Children with autism spectrum disorder (ASD) can suffer from immune dysregulation and inflammation, and now, a STEM CELLS Translational Medicine article from the lab of Neil H. Riordan (Meristem Panama, Inc., Clayton/Stem Cell Institute, Panama, Republic of Panama) reports on a recent trial of mesenchymal stem cells derived from the umbilical cord (UC-MSCs) as a potential treatment option. The authors report the safety and tolerability of UC-MSCs in autistic children, with a significant proportion demonstrating notable improvements of symptoms as measured by standardized autism diagnosis tools. However, the authors note that these encouraging results must be confirmed in a larger cohort of patients.