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Stem Cell Extracellular Vesicles Mediate Corneal Regeneration

Researchers led by James L. Funderburgh (University of Pittsburgh, Pittsburgh, Pennsylvania, USA) recently sought to understand the mechanisms by which corneal stromal stem cells enhance corneal wounding by assessing extracellular vesicles. In their new STEM CELLS Translational Medicine article, Shojaati et al. report that the delivery of miRNA to ocular tissues by extracellular vesicles leads to corneal regeneration. The authors hope that their findings will lead to the development of a rapid and inexpensive means of treating corneal blindness for millions of individuals who have no further options for treatment.