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Secretome in Ligament or Tendon Healing

Many therapeutic approaches have been evaluated for the treatment of tendon or ligament tear injuries, which can significantly affect the patient’s quality of life. While studies have provided evidence for mesenchymal stem cells (MSCs) as an effective therapeutic strategy for the treatment of tendon or ligament tears, we currently lack a full assessment of the role of the MSC secretome. Now, a new STEM CELLS Translational Medicine review article from Sholahuddin Rhatomy (Dr. Soeradji Tirtonegoro General Hospital, Klaten, Indonesia) discusses the preclinical evidence linking improvements in the tendon and ligament healing process with factors in the MSC secretome.