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Organoid Technology – A Review

A new STEM CELLS concise review from researchers led by Abbas Amini (Australian College of Kuwait, Kuwait/Western Sydney University, Australia) and Elham Bidram (University of Medical Sciences, Isfahan, Iran) discusses concerns regarding organoids, the methods available for in vitro organoid formation, and the different types of reported human organoid models. Shariati et al. also summarize biological approaches to improve the complexity of 3D organoids and therapeutic potentials of organoids. The review article comprehensively and critically presents this technology from different aspects, provides a systematic overview of the past and current applications of organoids, discusses the future perspectives, and provides suggestions to improve this technology and its applications.