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NCSCs in Tissue Regeneration

The multipotency of neural crest stem cells (NCSCs), a transient population of cells that arise during early vertebrate development and harbor stem cell‐like properties, enables the generation of a diverse population of cells, thereby making NCSCs a valuable cell source for tissue regeneration, disease modeling, and drug discovery. NCSCs can be derived from pluripotent stem cells, placental tissues, and adult tissues and generated via somatic cell reprogramming for tissue engineering and regenerative medicine applications. In a recent STEM CELLS Translational Medicine review, researchers led by Song Li (University of California Los Angeles, USA) present recent developments on the various approaches to derive NCSCs and their therapeutic application for tissue regeneration.