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Microglial Involvement in Multiple Sclerosis

A recent STEM CELLS review article from Foteini Tsouki and Anna Williams (University of Edinburgh, UK) summarizes our current knowledge regarding microglial involvement in the gray matter changes observed in multiple sclerosis (MS), given evidence implicating microglia in pathology, neuroprotection, and repair. Furthermore, the authors describe the ongoing development of potential therapeutic applications in MS that can harness microglia to protect and regenerate the central nervous system.