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Microfluidics and Autologous Cell Replacement

In a new STEM CELLS Translational Medicine article, researchers led by Todd Sulchek (Georgia Institute of Technology, Atlanta, GA) and Budd A. Tucker (University of Iowa, Iowa City, IA, USA) discuss the application of state-of-the-art microfluidic devices to stem cell transfection and post-differentiation cell enrichment (specifically, to the development of photoreceptor cells from induced pluripotent stem cells [iPSCs]). Stone et al. discuss how microfluidic approaches avoid using specialized reagents, reduce the regulatory burden, and address manufacturing challenges associated with autologous cell replacement.