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Metabolism in Cancer Immunoediting

A Concise Review from Irina Kareva (EMD Serono, Merck KGaA, Billerica, MA, USA) summarizes how immunometabolism may allow cancer cells to escape from the immune system, a process also known as immunoediting, while also highlighting the emerging role of gut microbiota and their effect on the immune system and response to immunotherapy. Furthermore, this recently published STEM CELLS article also discusses how these pieces can be integrated to devise better combination therapies and highlight the role of computational approaches as a potential tool to aid in combination therapy design.