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Mesenchymal Stem Cells for Urinary Incontinence

Researchers led by Mariano Garcia‐Arranz (Universidad Autónoma de Madrid, Madrid, Spain) aimed to evaluate the safety and feasibility of adipose‐derived mesenchymal stem cells to endoscopically treat urinary incontinence after radical prostatectomy in men or female stress urinary through designed two prospective, non-randomized phase I/IIa clinical trials. Their results, reported recently in STEM CELLS Translational Medicine, establish the intraurethral application of stem cells derived from adipose tissue as a safe and feasible means to treat urinary incontinence after radical prostatectomy or in female stress urinary incontinence. The authors now hope to confirm safety and to analyze efficacy in their subsequent research.