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Limbal Stem Cell Versus Tissue Transplantation

Researchers led by Vincent M. Borderie (Sorbonne Université, France) recently reported on a comparison of autologous or allogeneic cultured limbal stem cell transplantation and autologous or allogeneic limbal tissue transplantation for the treatment of stage III limbal stem cell deficiency. In their new STEM CELLS Translational Medicine article, the authors noted that autologous cultured limbal stem cell transplantation associated with high long‐term survival, vision improvement, and overall safety, whereas limbal grafts featured low safety, and allogeneic grafts featured low success rate and serious adverse events.